SCHEMBL1023729

SCHEMBL1023729

NN(S)C(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.48
TSHR P16473 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
CYP3A4 P08684 2/20 0.48
MAPT P10636 2/20 0.48
CA2 P00918 2/20 0.48
CA4 P22748 2/20 0.48
POLB P06746 2/20 0.48
PARP1 P09874 1/20 0.48
CYP2C19 P33261 1/20 0.48
RECQL P46063 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA3 P07451 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7524158 0.80 CA2 (0.52) TDP1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL64274 0.80 TDP1 (0.52) TDP1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL3720381 0.80 TDP1 (0.52) TDP1TSHRL3MBTL1CYP3A4MAPT
Fluoride SCHEMBL27802645 0.78 CA2 (0.50) TDP1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL2362058 0.78 TDP1 (0.50) TDP1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL10999012 0.78 CA2 (0.50) TDP1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL1620288 0.77 TDP1 (0.50) TDP1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL10441168 0.76 TDP1 (0.48) TDP1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL2146344 0.76 TDP1 (0.48) TDP1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL10990339 0.76 CA2 (0.48) TDP1TSHRL3MBTL1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1608623-B1 METAL ION CHELATORS AND THERAPEUTIC USE THEREOF RICHARDSON DESI RAYMOND (AU) 2011-01-19 EP claimed
CN-119673746-A Paper-based electrospray mass spectrometry ion source and preparation method and application thereof 北京中医药大学东方医院 2025-03-21 CN disclosed
CN-105636957-B Terazololine-one compound and application thereof 住友化学株式会社 2018-05-11 CN disclosed
CN-106800566-A Spiro indole ketone compounds, preparation method, pharmaceutical composition and purposes 中国科学院上海有机化学研究所 2017-06-06 CN disclosed
CN-101506154-B Compounds for treating proliferative disorders SYNTA PHARMACEUTICALS CORP 2015-06-17 CN disclosed