SCHEMBL64274

SCHEMBL64274

NN(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.52
TSHR P16473 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
CYP3A4 P08684 2/20 0.52
MAPT P10636 2/20 0.52
POLB P06746 2/20 0.52
PARP1 P09874 1/20 0.52
CYP2C19 P33261 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
PMP22 Q01453 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CES1 P23141 3/20 0.50
ALDH1A1 P00352 3/20 0.50
CES2 O00748 2/20 0.50
DAO P14920 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
CA2 P00918 2/20 0.46
CA4 P22748 2/20 0.46
CA12 O43570 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30629348 0.93 TDP1 (0.48) TDP1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL11680003 0.91 L3MBTL1 (0.52) TDP1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL9720219 0.91 TSHR (0.44) TDP1TSHRL3MBTL1CYP3A4MAPT
Terephthalic Acid SCHEMBL27838304 0.91 TSHR (0.61) TDP1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL11322544 0.90 TDP1 (0.48) TDP1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL2146344 0.90 TDP1 (0.48) TDP1TSHRL3MBTL1CYP3A4MAPT
Succinic Acid SCHEMBL27852517 0.89 NR4A2 (0.57) TDP1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL27963230 0.89 MEN1 (0.47) TDP1TSHRL3MBTL1CYP3A4MAPT
Malonic Acid SCHEMBL27909909 0.89 TDP1 (0.46) TDP1TSHRL3MBTL1CYP3A4MAPT
SCHEMBL5574638 0.88 TSHR (0.52) TDP1TSHRL3MBTL1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 557 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119529341-A Moisture-heat-resistant polylactic acid transparent film and preparation method thereof 广东省国科海纳新材料科技有限公司 2025-02-28 CN claimed
CN-119529342-A Transparent heat-curl-resistant polylactic acid film and preparation method thereof 广东省国科海纳新材料科技有限公司 2025-02-28 CN claimed
CN-115748007-B Modified polylactic acid tow 浙江兴邦新材料科技有限公司 2024-07-30 CN claimed
CN-115558070-B Compatilizer suitable for modification processing of biodegradable material, preparation and application thereof 美瑞新材料股份有限公司 2024-03-12 CN claimed
CN-115960593-B Degradable temporary plugging agent suitable for shallow low-temperature reservoir fracturing and preparation method and application thereof 中国石油天然气股份有限公司 2024-01-30 CN claimed
CN-116855046-A PLA/PPC-based biodegradable material and preparation method thereof 沈阳化工大学 2023-10-10 CN claimed
CN-116836528-A Quick-crystallization polylactic acid-based wood-plastic composite material and preparation method thereof 中国林业科学研究院木材工业研究所 2023-10-03 CN claimed
CN-114941185-B Polylactic acid fiber artificial muscle and preparation method thereof 四川大学 2023-03-21 CN claimed
CN-115748007-A Modified polylactic acid tow 安徽英特力工业工程技术有限公司 2023-03-07 CN claimed
CN-112708250-B High-permeability high-barrier polylactic acid material and preparation method and application thereof 湖南省菱越新材料有限公司(CN) 2023-01-13 CN claimed
US-20090248147-A1 Stent With Nucleating Agent ABBOTT CARDIOVASCULAR SYSTEMS INC 2009-10-01 US claimed
US-20070292967-A1 Assay for Ligands of the Ecdysone Receptor COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) 2007-12-20 US claimed
EP-1720894-A1 ASSAY FOR LIGANDS OF THE ECDYSONE RECEPTOR COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2006-11-15 EP claimed
US-20060240088-A1 Caged ligands and uses thereof ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2006-10-26 US claimed
WO-2005054271-A1 ASSAY FOR LIGANDS OF THE ECDYSONE RECEPTOR COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2005-06-16 WO claimed
WO-2004037983-A2 CAGED LIGANDS AND USES THEREOF ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2004-05-06 WO claimed
CN-1472196-A Bibenzoyl diamide compounds and their uses 江苏克胜集团股份有限公司 2004-02-04 CN claimed
CN-1435411-A Process for preparing N.N'-diacyl-N'-t-butyl hydrazine ZHELUSE TECH CO LTD ZHUHAI (CN) 2003-08-13 CN claimed
CN-1109049-A Preparation of 1,2-diacyl-2-(T-alkyl) hydrazines ROHM & HAAS (US) 1995-09-27 CN claimed
CN-1107290-A Turfgrass insecticides ROHM & HAAS (US) 1995-08-30 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070292967-A1 Assay for Ligands of the Ecdysone Receptor OR51E2, FSHR, ESRRB TDP1 4727/4885TSHR 156/4885L3MBTL1 1425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.