Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.42 |
| ▸ | POLG | P54098 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15865915 | 0.84 | PDE3A (0.39) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL10239773 | 0.76 | LMNA (0.42) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL23105029 | 0.75 | POLG (0.40) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL25647918 | 0.75 | POLG (0.40) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL10239455 | 0.74 | STING1 (0.64) | STING1 | |
| SCHEMBL22589427 | 0.73 | FGFR1 (0.51) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL24625409 | 0.73 | FGFR1 (0.51) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL25416164 | 0.72 | LMNA (0.39) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL23610456 | 0.70 | STING1 (0.42) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL30404892 | 0.70 | POLG (0.37) | LMNAPDE3ACACNA1FALBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088155-A1 | CYCLIC NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2012-06-28 | — | — | WO | disclosed |