SCHEMBL1024000

SCHEMBL1024000

CCCCCCCCCCCCCCCCCCCCCC(=O)OCCOCCOCC

nearest known ligand 0.78

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.78
DNM1 Q05193 1/20 0.59
PAM P19021 2/20 0.55
EPHX2 P34913 2/20 0.53
TSHR P16473 2/20 0.51
MAPT P10636 1/20 0.51
PRSS1 P07477 1/20 0.51
PRSS2 P07478 1/20 0.51
PRSS3 P35030 1/20 0.51
LMNA P02545 2/20 0.50
ALDH1A1 P00352 2/20 0.50
NAAA Q02083 1/20 0.50
KDM4E B2RXH2 1/20 0.49
DUSP3 P51452 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
HTR2C P28335 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22130352 1.00 DGKA (0.78) DGKADNM1PAMEPHX2TSHR
SCHEMBL22130337 1.00 DGKA (0.78) DGKADNM1PAMEPHX2TSHR
SCHEMBL5171427 1.00 DGKA (0.78) DGKADNM1PAMEPHX2TSHR
SCHEMBL22130348 1.00 DGKA (0.78) DGKADNM1PAMEPHX2TSHR
SCHEMBL22130350 1.00 DGKA (0.78) DGKADNM1PAMEPHX2TSHR
SCHEMBL11759279 1.00 DGKA (0.78) DGKADNM1PAMEPHX2TSHR
SCHEMBL9615289 1.00 DGKA (0.78) DGKADNM1PAMEPHX2TSHR
SCHEMBL22130347 1.00 DGKA (0.78) DGKADNM1PAMEPHX2TSHR
SCHEMBL9740709 0.98 DGKA (0.74) DGKADNM1PAMEPHX2TSHR
SCHEMBL22130349 0.98 DGKA (0.81) DGKADNM1PAMEPHX2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2214634-B1 EXTERNAL PREPARATIONS FOR MOSTURIZING THE SKIN CONTAINING LITSEA POLYANTHA ANBAS CORP (JP) 2014-04-30 EP disclosed
CN-102485196-A Hair dye IKEDA DENSO MATERIAL CO LTD 2012-06-06 CN disclosed
US-20120093896-A1 USE OF NANODISPERSIONS TO PROTECT WATER-SOLUBLE INGREDIENTS IN COSMETIC END FORMULATIONS CIBA CORPORATION (US) 2012-04-19 US disclosed
CN-102088956-A Use of proguanil for treating skin/mucosal disorders TOLMAR INC 2011-06-08 CN disclosed
EP-2273974-A2 PROGUANIL TO TREAT SKIN/MUCOSAL DISEASES Tolmar, Inc. (US) 2011-01-19 EP disclosed
EP-1807120-B2 WETTING AGENT BASED ON A MIXTURE OF MONOESTERS AND DIESTERS OF BUTYLENE GLYCOL GATTEFOSSE SAS (FR) 2010-11-10 EP disclosed
US-20100255123-A1 SKIN MOISTURIZER, BLOOD CIRCULATION PROMOTER, AND EXTERNAL PREPARATIONS FOR THE SKIN CONTAINING THE SKIN MOISTURIZER AND THE BLOOD CIRCULATION PROMOTER POONSOOK LOHAJOTI (TH) 2010-10-07 US disclosed
EP-2214634-A1 SKIN MOISTURIZER, BLOOD CIRCULATION PROMOTER, AND EXTERNAL PREPARATIONS FOR THE SKIN CONTAINING THE SKIN MOISTURIZER AND THE BLOOD CIRCULATION PROMOTER Anbas Corporation (JP) 2010-08-11 EP disclosed
US-20100111884-A1 UV ABSORBER FORMULATIONS CIBA CORPORATION (US) 2010-05-06 US disclosed
EP-2170250-A1 USE OF NANODISPERSIONS TO PROTECT WATER-SOLUBLE INGREDIENTS IN COSMETIC END FORMULATIONS BASF SE (DE) 2010-04-07 EP disclosed
WO-2007137958-A2 SELF TANNING COMPOSITION CIBA HOLDING INC. (CH) 2007-12-06 WO disclosed
US-20070196528-A1 Cosmetic composition based on caper flower bud extract GATTEFOSSE S.A.S. (FR) 2007-08-23 US disclosed
EP-1408912-B1 TEMPERATURE INSENSITIVE ONE-PHASE MICROEMULSIONS DOW CORNING (US) 2007-03-07 EP disclosed
US-20060204526-A1 Emulsive composition containing Dapsone ALLERGAN, INC. 2006-09-14 US disclosed
WO-2006071584-A2 RELEASE PARTICLE COMPOSITION, PROCESS FOR MAKING SAME, AND COMPOSITION HAVING SUCH PARTICLES AVON PRODUCTS INC. (US) 2006-07-06 WO disclosed
EP-1675563-A1 EMULSIVE COMPOSITION CONTAINING DAPSONE QLT USA, Inc. (US) 2006-07-05 EP disclosed
WO-2005016296-A1 EMULSIVE COMPOSITION CONTAINING DAPSONE QLT USA, INC. (US) 2005-02-24 WO disclosed
EP-1408912-A2 TEMPERATURE INSENSITIVE ONE-PHASE MICROEMULSIONS Dow Corning Corporation (US) 2004-04-21 EP disclosed
WO-2003009819-A2 TEMPERATURE INSENSITIVE ONE-PHASE MICROEMULSIONS DOW CORNING CORPORATION (US) 2003-02-06 WO disclosed
US-6498197-B1 Temperature insensitive one-phase microemulsions DOW CORNING CORPORATION 2002-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100111884-A1 UV ABSORBER FORMULATIONS C1R, C1S, C9 DGKA 4376/4885DNM1 4010/4885PAM 570/4885
US-20120093896-A1 USE OF NANODISPERSIONS TO PROTECT WATER-SOLUBLE INGREDIENTS IN COSMETIC END FORMULATIONS CUTA, PROC, RBP1 DGKA 175/4885DNM1 3707/4885PAM 3749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.