SCHEMBL1024054

SCHEMBL1024054

C=C(C)C(=O)OCCCCCCCCCCC[Si](C)(OC)OC

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
THRB P10828 1/20 0.44
ALDH1A1 P00352 4/20 0.39
CYP3A4 P08684 1/20 0.33
ACHE P22303 6/20 0.33
NAAA Q02083 1/20 0.32
RAD52 P43351 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16207814 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL3503229 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16223550 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16223447 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16223339 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16207722 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL3503198 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16223397 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16223446 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL978173 0.98 TSHR (0.58) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113526934-B 3D printing graphene oxide reinforced cement-based material and preparation method thereof 中科峰达(黑龙江)新材料科技有限公司 2022-08-23 CN claimed
CN-113526934-A 3D printing graphene oxide reinforced cement-based material and preparation method thereof 梁英 2021-10-22 CN claimed
US-20200155421-A1 TWO-PASTE DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2020-05-21 US claimed
EP-3646847-A1 TWO-PASTE TYPE DENTAL CURABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2020-05-06 EP claimed
EP-3669854-B1 PHOTOPOLYMERIZABLE DENTAL COMPOSITION G C DENTAL IND CORP (JP) 2026-04-08 EP disclosed
EP-3141581-B1 RESIN COMPOSITE MATERIAL AND METHOD FOR MANUFACTURING RESIN COMPOSITE MATERIAL TOKUYAMA DENTAL CORP (JP) 2025-11-05 EP disclosed
WO-2025126917-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2025-06-19 WO disclosed
EP-3373887-B1 KIT OF PARTS FOR PRODUCING A GLASS IONOMER CEMENT, PROCESS OF PRODUCTION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-11-27 EP disclosed
US-20240174780-A1 HOLLOW PARTICLES AND USE THEREOF SEKISUI KASEI CO., LTD. (JP) 2024-05-30 US disclosed
EP-3586814-B1 DENTAL CURABLE COMPOSITION G C DENTAL IND CORP (JP) 2024-01-31 EP disclosed
US-11883790-B2 Hollow particles, method for producing same, and usage of same SEKISUI KASEI CO., LTD. (JP) 2024-01-30 US disclosed
US-11446214-B2 Curable dental composite GC CORPORATION (JP) 2022-09-20 US disclosed
CN-101600412-B Curable composition for dental use KURARAY MEDICAL INC JP 2012-12-12 CN disclosed
CN-102083403-A Dental composition and composite resin KURARAY MEDICAL INC 2011-06-01 CN disclosed
US-7951851-B2 Curable composition for dental purposes KURARAY MEDICAL INC. (JP) 2011-05-31 US disclosed
US-20110046261-A1 DENTAL COMPOSITION AND COMPOSITE RESIN KURARAY MEDICAL INC. (JP) 2011-02-24 US disclosed
EP-2275076-A1 DENTAL COMPOSITION AND COMPOSITE RESIN Kuraray Medical Inc. (JP) 2011-01-19 EP disclosed
US-20100105802-A1 CURABLE COMPOSITION FOR DENTAL PURPOSES KURARAY MEDICAL INC. (JP) 2010-04-29 US disclosed
CN-101600412-A Curable composition for dental use KURARAY MEDICAL INC (JP) 2009-12-09 CN disclosed
EP-2123247-A1 CURABLE COMPOSITION FOR DENTAL PURPOSES Kuraray Medical Inc. (JP) 2009-11-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105802-A1 CURABLE COMPOSITION FOR DENTAL PURPOSES H1-0, H1-3, H1-2 TSHR 2517/4885POLB 696/4885APEX1 1834/4885
US-20110046261-A1 DENTAL COMPOSITION AND COMPOSITE RESIN CAD, KATNAL2, ZYX TSHR 3309/4885POLB 623/4885APEX1 4096/4885
US-20200155421-A1 TWO-PASTE DENTAL CURABLE COMPOSITION CAD, DNMT3A, DNMT3B TSHR 4487/4885POLB 351/4885APEX1 3101/4885
US-11446214-B2 Curable dental composite VCL, CORO1A, ACTB TSHR 3573/4885POLB 588/4885APEX1 3501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.