Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16207814 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3503229 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16223550 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16223447 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16223339 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1024054 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16207722 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16223397 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16223446 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL978173 | 0.98 | TSHR (0.58) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200155421-A1 | TWO-PASTE DENTAL CURABLE COMPOSITION | KURARAY NORITAKE DENTAL INC. (JP) | 2020-05-21 | — | — | US | claimed |
| EP-3646847-A1 | TWO-PASTE TYPE DENTAL CURABLE COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2020-05-06 | — | — | EP | claimed |
| EP-3141581-B1 | RESIN COMPOSITE MATERIAL AND METHOD FOR MANUFACTURING RESIN COMPOSITE MATERIAL | TOKUYAMA DENTAL CORP (JP) | 2025-11-05 | — | — | EP | disclosed |
| WO-2025053161-A1 | SURFACE-TREATED ALUMINUM NITRIDE POWDER | 株式会社トクヤマ | 2025-03-13 | — | — | WO | disclosed |
| US-20240174780-A1 | HOLLOW PARTICLES AND USE THEREOF | SEKISUI KASEI CO., LTD. (JP) | 2024-05-30 | — | — | US | disclosed |
| US-11883790-B2 | Hollow particles, method for producing same, and usage of same | SEKISUI KASEI CO., LTD. (JP) | 2024-01-30 | — | — | US | disclosed |
| US-11369935-B2 | Hollow particles and use thereof | SEKISUI PLASTICS CO., LTD. (JP) | 2022-06-28 | — | — | US | disclosed |
| EP-3766571-A1 | HOLLOW PARTICLES, METHOD FOR PRODUCING SAME, AND USAGE OF SAME | SEKISUI KASEI CO., LTD. (JP) | 2021-01-20 | — | — | EP | disclosed |
| US-20210001300-A1 | HOLLOW PARTICLES, METHOD FOR PRODUCING SAME, AND USAGE OF SAME | SEKISUI KASEI CO., LTD. (JP) | 2021-01-07 | — | — | US | disclosed |
| US-20200155421-A1 | TWO-PASTE DENTAL CURABLE COMPOSITION | KURARAY NORITAKE DENTAL INC. (JP) | 2020-05-21 | — | — | US | disclosed |
| EP-3646847-A1 | TWO-PASTE TYPE DENTAL CURABLE COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2020-05-06 | — | — | EP | disclosed |
| US-20100210745-A1 | Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes | REACTIVE SURFACES, LTD. (US) | 2010-08-19 | — | — | US | disclosed |
| EP-1226807-B1 | DENTAL CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2008-08-13 | — | — | EP | disclosed |
| EP-1236459-B1 | PHOTO-CURABLE REPARATIVE MATERIAL FOR DENTAL USE | TOKUYAMA CORP (JP) | 2005-11-23 | — | — | EP | disclosed |
| US-6933327-B2 | Dental curable composition | TOKUYAMA CORPORATION (JP) | 2005-08-23 | — | — | US | disclosed |
| US-6849670-B2 | Photo-curable reparative material for dental use | TOKUYAMA CORPORATION (JP) | 2005-02-01 | — | — | US | disclosed |
| US-20030162863-A1 | Photo-curable reparative material for dental use | TOKUYAMA CORPORATION (JP) | 2003-08-28 | — | — | US | disclosed |
| US-20030036582-A1 | Dental curable composition | TOKUYAMA CORPORATION (JP) | 2003-02-20 | — | — | US | disclosed |
| EP-1236459-A1 | PHOTO-CURABLE REPARATIVE MATERIAL FOR DENTAL USE | TOKUYAMA CORPORATION (JP) | 2002-09-04 | — | — | EP | disclosed |
| EP-1226807-A1 | DENTAL CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2002-07-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162863-A1 | Photo-curable reparative material for dental use | MBTD1, AP3M1, MYO1G | TSHR 3616/4885POLB 737/4885APEX1 35/4885 |
| US-20200155421-A1 | TWO-PASTE DENTAL CURABLE COMPOSITION | CAD, DNMT3A, DNMT3B | TSHR 4487/4885POLB 351/4885APEX1 3101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.