SCHEMBL1024142

SCHEMBL1024142

Nc1ccc(Cl)c2ccccc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 2/20 0.73
CYP2A6 P11509 4/20 0.68
CYP1A2 P05177 3/20 0.68
TSHR P16473 4/20 0.52
CYP3A4 P08684 3/20 0.52
ALDH1A1 P00352 2/20 0.52
HPGD P15428 2/20 0.52
HSD17B10 Q99714 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
IDO1 P14902 2/20 0.52
EP300 Q09472 2/20 0.52
KAT8 Q9H7Z6 2/20 0.52
HDAC3 O15379 1/20 0.52
KAT2B Q92831 1/20 0.52
NCOR2 Q9Y618 1/20 0.52
KMT2A Q03164 2/20 0.48
ATM Q13315 1/20 0.48
CHEK1 O14757 1/20 0.46
NEK2 P51955 1/20 0.46
LIMK1 P53667 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31499475 1.00 NR4A2 (0.73) NR4A2CYP2A6CYP1A2TSHRCYP3A4
SCHEMBL29418802 0.84 NR4A2 (1.00) NR4A2CYP2A6CYP1A2TSHRCYP3A4
SCHEMBL3183644 0.84 NR4A2 (1.00) NR4A2CYP2A6CYP1A2TSHRCYP3A4
SCHEMBL29404342 0.83 ALDH1A1 (0.73) NR4A2TSHRCYP3A4ALDH1A1HPGD
SCHEMBL2473555 0.83 CYP2A6 (1.00) NR4A2CYP2A6CYP1A2TSHRALDH1A1
SCHEMBL201893 0.83 ALDH1A1 (0.73) NR4A2TSHRCYP3A4ALDH1A1HPGD
SCHEMBL29494605 0.83 CYP2A6 (1.00) NR4A2CYP2A6CYP1A2TSHRALDH1A1
Hydrochloric Acid SCHEMBL7191297 0.80 CYP3A4 (0.69) NR4A2TSHRCYP3A4ALDH1A1HPGD
SCHEMBL21854609 0.77 ALDH1A1 (0.87) NR4A2TSHRCYP3A4ALDH1A1HPGD
SCHEMBL9404198 0.75 NR4A2 (0.60) NR4A2CYP2A6CYP1A2TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119510639-A Method for detecting 2 chloronaphthylamines in drinking water by gas chromatography-mass spectrometry 苏州见远检测技术有限公司 2025-02-25 CN claimed
CN-119059874-A Synthesis method of 3-bromo-1-chloronaphthalene 棓诺(苏州)新材料有限公司 2024-12-03 CN claimed
CN-115368292-A Benzoindole compound and synthetic method thereof 陕西科技大学 2022-11-22 CN claimed
EP-1773768-A4 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2008-08-06 EP claimed
EP-1773768-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS Exelixis, Inc. (US) 2007-04-18 EP claimed
WO-2006012642-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS, INC. (US) 2006-02-02 WO claimed
JP-2002544186-A 2002-12-24 JP claimed
US-6417195-B1 LIBRARIES AND COMBINATORIAL CHEMISTRY LION BIOSCIENCE AG (DE) 2002-07-09 US claimed
EP-1178953-A1 AROMATIC AMIDES WARNER-LAMBERT COMPANY (US) 2002-02-13 EP claimed
WO-2000068184-A1 AROMATIC AMIDES WARNER-LAMBERT COMPANY (US) 2000-11-16 WO claimed
US-5916899-A SOLID PHASE SYNTHESIS, REACTING PROTECTED AMINO ACID WITH SOLID SUPPORT; FORMING IMINE BY REACTION WITH ALDEHYDE, CYCLIZATION WITH ANHYDRIDE, CLEAVAGE AND DEPROTECTION. TREGA BIOSCIENCES, INC. (US) 1999-06-29 US claimed
US-5874443-A BIOSYNTHESIS TREGA BIOSCIENCES, INC. (US) 1999-02-23 US claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
US-20260062412-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY CHUGAI PHARMACEUTICAL CO LTD (JP) 2026-03-05 US disclosed
EP-4647424-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-11-12 EP disclosed
CN-119510639-A Method for detecting 2 chloronaphthylamines in drinking water by gas chromatography-mass spectrometry 苏州见远检测技术有限公司 2025-02-25 CN disclosed
EP-0102680-B1 SUBSTITUTED N-(2,4-DINITRO-6-(TRIFLUOROMETHYL)PHENYL)-NAPHTHALENAMINE DERIVATIVES ELI LILLY AND COMPANY (US) 1986-03-05 EP disclosed
EP-0102680-A1 Substituted N-(2,4-dinitro-6-(trifluoromethyl)phenyl)-naphthalenamine derivatives ELI LILLY AND COMPANY (US) 1984-03-14 EP disclosed
US-4423065-A MITICIDES, PARASITICIDES ELI LILLY AND COMPANY (US) 1983-12-27 US disclosed
US-3931340-A Chlorination of aromatic compounds ASAHI DENKA KOGYO K.K. (JA) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062412-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY MYT1, NTMT1, MYL6 NR4A2 2643/4885CYP2A6 2185/4885CYP1A2 3172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.