SCHEMBL10241543

SCHEMBL10241543

COC(=O)c1nc(-c2ccc(Cl)c(C(C)O)c2F)cc(N)c1Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.37
PKM P14618 2/20 0.37
RCE1 Q9Y256 1/20 0.37
ALPL P05186 3/20 0.36
NQO2 P16083 2/20 0.35
SCN10A Q9Y5Y9 1/20 0.34
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ABL1 P00519 2/20 0.32
S1PR4 O95977 1/20 0.32
MET P08581 3/20 0.32
KDR P35968 2/20 0.32
AURKA O14965 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
YES1 P07947 1/20 0.32
FGFR2 P21802 1/20 0.32
EPHA2 P29317 1/20 0.32
LTK P29376 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3329108 0.93 KDM4E (0.38) KDM4EPKMRCE1ALPLNQO2
SCHEMBL10241443 0.91 KDM4E (0.36) KDM4EPKMRCE1ALPLNQO2
SCHEMBL3324901 0.90 KDM4E (0.38) KDM4EPKMRCE1ALPLNQO2
SCHEMBL3331735 0.88 KDM4E (0.36) KDM4EPKMRCE1ALPLNQO2
SCHEMBL3330786 0.87 KDM4E (0.35) KDM4EPKMRCE1ALPLNQO2
SCHEMBL3329176 0.85 ALPL (0.40) KDM4EPKMRCE1ALPLNQO2
SCHEMBL115368 0.84 KDM4E (0.40) KDM4EPKMRCE1ALPLNQO2
SCHEMBL3328979 0.84 KDM4E (0.40) KDM4EPKMRCE1ALPLNQO2
SCHEMBL29423657 0.84 KDM4E (0.40) KDM4EPKMRCE1ALPLNQO2
SCHEMBL3324876 0.84 KDM4E (0.40) KDM4EPKMRCE1ALPLNQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012052410-A1 NOVEL SUBSTITUTED PICOLINIC ACIDS, SALTS AND ACID DERIVATIVES THEREOF, AND USE THEREOF AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2012-04-26 WO disclosed