Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2696445 | 0.83 | MET (1.00) | MET | |
| SCHEMBL19191585 | 0.74 | MET (0.83) | METKCNH2 | |
| SCHEMBL10242434 | 0.72 | MET (0.75) | METKCNH2 | |
| SCHEMBL3259392 | 0.72 | MET (0.71) | MET | |
| SCHEMBL12877881 | 0.71 | MET (0.56) | METKCNH2 | |
| SCHEMBL1163189 | 0.71 | MET (0.57) | METKCNH2 | |
| SCHEMBL9910350 | 0.70 | MET (1.00) | MET | |
| SCHEMBL1656793 | 0.70 | MET (0.74) | MET | |
| SCHEMBL18885768 | 0.69 | MET (0.53) | METKCNH2 | |
| SCHEMBL27824234 | 0.69 | MET (0.53) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107275-A1 | FUSED HETEROCYCLIC DERIVATIVES AND METHODS OF USE | AMGEN INC. (US) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107275-A1 | FUSED HETEROCYCLIC DERIVATIVES AND METHODS OF USE | HGF, HGFAC, MET | MET 3/4885KCNH2 4715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.