Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | DDX3X | O00571 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417463 | 1.00 | MEN1 (0.44) | MEN1KMT2ANPC1MITFGAA | |
| SCHEMBL416612 | 1.00 | MEN1 (0.44) | MEN1KMT2ANPC1MITFGAA | |
| SCHEMBL411926 | 0.94 | MEN1 (0.41) | MEN1KMT2ANPC1MITFGAA | |
| SCHEMBL17836763 | 0.94 | MEN1 (0.41) | MEN1KMT2ANPC1MITFGAA | |
| SCHEMBL411927 | 0.94 | MEN1 (0.41) | MEN1KMT2ANPC1MITFGAA | |
| SCHEMBL10241983 | 0.91 | DDX3X (0.48) | MEN1KMT2ANPC1MITFGAA | |
| SCHEMBL415825 | 0.91 | DDX3X (0.48) | MEN1KMT2ANPC1MITFGAA | |
| SCHEMBL415846 | 0.91 | DDX3X (0.48) | MEN1KMT2ANPC1MITFGAA | |
| SCHEMBL17836748 | 0.88 | LRRK2 (0.49) | MEN1KMT2ANPC1MITFGAA | |
| SCHEMBL415720 | 0.88 | LRRK2 (0.49) | MEN1KMT2ANPC1MITFGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | disclosed |
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | disclosed |
| WO-2012012528-A1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | Vestaron Corporation (US) | 2012-01-26 | — | — | WO | disclosed |