Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | IDH2 | P48735 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415830 | 1.00 | LRRK2 (0.49) | LRRK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL415720 | 1.00 | LRRK2 (0.49) | LRRK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10241983 | 0.90 | DDX3X (0.48) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL415846 | 0.90 | DDX3X (0.48) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL415825 | 0.90 | DDX3X (0.48) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL416612 | 0.88 | MEN1 (0.44) | LRRK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL417463 | 0.88 | MEN1 (0.44) | LRRK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10242562 | 0.88 | MEN1 (0.44) | LRRK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL414775 | 0.85 | CHRNA7 (0.51) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL10242560 | 0.85 | CHRNA7 (0.51) | NPC1RAB9AMEN1KMT2AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | disclosed |