SCHEMBL10242702

SCHEMBL10242702

C=C(C)C(=O)OC1C2OC(=O)C3CC4C[C@@]41C32

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
RAB9A P51151 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GPX4 P36969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169869 1.00 KDM4E (0.32) KDM4ENPC1POLBMAPTPKM
SCHEMBL172034 0.87 KDM4E (0.32) KDM4ENPC1POLBMAPTPKM
SCHEMBL10244020 0.80 KDM4E (0.31) KDM4ENPC1POLBMAPTPKM
SCHEMBL13383461 0.79
SCHEMBL16784705 0.76 ALDH1A1 (0.30)
SCHEMBL10064059 0.74 CYP3A4 (0.31) KDM4ENPC1POLBMAPTPKM
SCHEMBL685738 0.73 KDM4E (0.30) KDM4ENPC1POLBMAPTPKM
SCHEMBL1320977 0.72
SCHEMBL10027337 0.72 ABCB1 (0.32)
SCHEMBL10244269 0.71 ICAM1 (0.32) KDM4ENPC1POLBMAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2450746-A1 Positive resist composition and pattern forming method using the composition Fujifilm Corporation (JP) 2012-05-09 EP disclosed
EP-2192134-A1 PHOTOSENSITIVE COMPOSITION, PATTERN-FORMING METHOD USING THE PHOTOSENSITIVE COMPOSITION, AND COMPOUND USED IN THE PHOTOSENSITIVE COMPOSITION Fujifilm Corporation (JP) 2010-06-02 EP disclosed