Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LIPE | Q05469 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923497 | 0.86 | L3MBTL1 (0.49) | L3MBTL1HPGDKMT2AMAPTLIPE | |
| SCHEMBL876438 | 0.82 | L3MBTL1 (0.46) | L3MBTL1HPGDKMT2AMAPTLIPE | |
| SCHEMBL876080 | 0.79 | LIPE (0.57) | MAPTLIPEMAPK1SCN9ALMNA | |
| SCHEMBL10243167 | 0.78 | L3MBTL1 (0.41) | L3MBTL1MAPTSMN1; SMN2LMNAATM | |
| SCHEMBL875200 | 0.76 | L3MBTL1 (0.54) | L3MBTL1HPGDKMT2AMAPTLIPE | |
| SCHEMBL9110252 | 0.76 | L3MBTL1 (0.64) | L3MBTL1HPGDKMT2AMAPTLIPE | |
| SCHEMBL28481117 | 0.76 | KMT2A (0.59) | L3MBTL1HPGDKMT2AMAPTLIPE | |
| SCHEMBL10246021 | 0.75 | L3MBTL1 (0.50) | L3MBTL1HPGDKMT2AMAPTMAPK1 | |
| SCHEMBL9105550 | 0.73 | L3MBTL1 (0.46) | L3MBTL1HPGDKMT2AMAPTLIPE | |
| SCHEMBL875974 | 0.72 | L3MBTL1 (0.50) | L3MBTL1HPGDKMT2AMAPTLIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037782-A1 | TRICYCLIC COMPOUNDS, PREPARATION METHODS, AND THEIR USES | GLAXO GROUP LIMITED (GB) | 2012-03-29 | — | — | WO | disclosed |