Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10243135 | 0.96 | APP (0.43) | APPHCRTR1BCHEACHEL3MBTL1 | |
| SCHEMBL10243117 | 0.91 | L3MBTL1 (0.41) | L3MBTL1 | |
| SCHEMBL10282710 | 0.87 | APP (0.43) | APPL3MBTL1 | |
| SCHEMBL10243705 | 0.84 | HCRTR1 (0.43) | HCRTR1L3MBTL1 | |
| SCHEMBL10245606 | 0.84 | CHRM2 (0.43) | APPBCHEACHECHRM2L3MBTL1 | |
| SCHEMBL10243108 | 0.83 | PPARG (0.47) | BCHEACHECHRM2 | |
| SCHEMBL10243168 | 0.83 | CHRM2 (0.48) | BCHEACHECHRM2 | |
| SCHEMBL10243344 | 0.82 | PPARG (0.49) | BCHEACHECHRM2 | |
| SCHEMBL10243139 | 0.81 | PPARG (0.46) | BCHEACHEL3MBTL1 | |
| SCHEMBL334443 | 0.81 | BCHE (0.47) | BCHEACHECHRM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281292-A1 | 10a-Azalide Compound | IL17A, AZI2, HDAC9 | APP 4678/4885HCRTR1 3325/4885BCHE 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.