SCHEMBL10243344

SCHEMBL10243344

CCN(CCCCCC(=O)OC)[C@@H](C)c1ccccc1OC

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.49
ACHE P22303 13/20 0.48
BCHE P06276 12/20 0.48
PPARA Q07869 2/20 0.42
CHRM2 P08172 2/20 0.41
CHRM1 P11229 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10243108 0.99 PPARG (0.47) PPARGACHEBCHEPPARACHRM2
SCHEMBL10243139 0.95 PPARG (0.46) PPARGACHEBCHEPPARA
SCHEMBL335831 0.89 ACHE (0.49) ACHEBCHECHRM2CHRM1
SCHEMBL334443 0.88 BCHE (0.47) ACHEBCHECHRM2CHRM1
SCHEMBL334644 0.84 LMNA (0.44) ACHEBCHE
SCHEMBL334643 0.84 LMNA (0.44) ACHEBCHE
SCHEMBL10245591 0.83 ACHE (0.41) ACHEBCHE
SCHEMBL10243410 0.82 HPGD (0.41) ACHEBCHECHRM2
SCHEMBL10243142 0.82 APP (0.43) ACHEBCHECHRM2
SCHEMBL10282710 0.81 APP (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281292-A1 10a-Azalide Compound IL17A, AZI2, HDAC9 PPARG 2159/4885ACHE 1324/4885BCHE 1393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.