Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | IDH2 | P48735 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 4/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10244355 | 0.94 | IDH2 (0.47) | APPLMNAMAPTMAPK1IDH2 | |
| SCHEMBL1395264 | 0.90 | LMNA (0.52) | APPLMNAMAPTMAPK1IDH2 | |
| SCHEMBL1395404 | 0.89 | APP (0.50) | APPLMNAMAPTMAPK1IDH2 | |
| SCHEMBL1395458 | 0.88 | LMNA (0.48) | APPLMNAMAPTMAPK1IDH2 | |
| SCHEMBL1395429 | 0.86 | APP (0.51) | APPLMNAMAPTMAPK1IDH2 | |
| SCHEMBL1392036 | 0.86 | IDH2 (0.50) | APPLMNAMAPTMAPK1IDH2 | |
| SCHEMBL1391563 | 0.86 | LMNA (0.56) | APPLMNAMAPTMAPK1IDH2 | |
| SCHEMBL1391773 | 0.85 | LMNA (0.47) | LMNAMAPTMAPK1IDH2MEN1 | |
| SCHEMBL1392288 | 0.85 | LMNA (0.49) | APPLMNAMAPTMAPK1IDH2 | |
| SCHEMBL1395285 | 0.85 | IDH2 (0.53) | APPLMNAMAPTMAPK1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009151-A1 | Triazines And Related Compounds Having Antiviral Activity, Compositions And Methods Thereof | PROGENICS PHARMACEUTICALS, INC. (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120009151-A1 | Triazines And Related Compounds Having Antiviral Activity, Compositions And Methods Thereof | PROGENICS PHARMACEUTICALS, INC. (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009151-A1 | Triazines And Related Compounds Having Antiviral Activity, Compositions And Methods Thereof | HAVCR2, ZC3HAV1, MAVS | APP 4146/4885LMNA 3218/4885MAPT 3654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.