SCHEMBL10244840

SCHEMBL10244840

CCNC(=O)CN(CC)[C@@H](C)c1ccccc1OC

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.42
HTT P42858 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ALDH1A1 P00352 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10282646 0.88 LMNA (0.41) HPGDHTTL3MBTL1MEN1KMT2A
SCHEMBL10243410 0.85 HPGD (0.41) HPGDHTTL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL10245022 0.80 CA1 (0.44) HTTL3MBTL1MEN1KMT2APOLB
SCHEMBL11886646 0.80 CA1 (0.44) HTTL3MBTL1MEN1KMT2APOLB
SCHEMBL10243117 0.78 L3MBTL1 (0.41) HPGDHTTL3MBTL1MEN1KMT2A
SCHEMBL10282559 0.78 HPGD (0.42) HPGDHTTL3MBTL1MEN1KMT2A
Trifluoroacetic Acid SCHEMBL335628 0.77 TAAR1 (0.40) HPGDHTTL3MBTL1KMT2ALMNA
Trifluoroacetic Acid SCHEMBL335630 0.77 TAAR1 (0.40) HPGDHTTL3MBTL1KMT2ALMNA
SCHEMBL10282710 0.76 APP (0.43) HPGDHTTL3MBTL1MEN1KMT2A
SCHEMBL10244546 0.76 L3MBTL1 (0.42) HPGDHTTL3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097708-B2 10a-Azalide compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2012-01-17 US disclosed
US-20090281292-A1 10a-Azalide Compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2009-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281292-A1 10a-Azalide Compound IL17A, AZI2, HDAC9 HPGD 556/4885HTT 868/4885L3MBTL1 2853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.