Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | USP5 | P45974 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15215001 | 0.93 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2ATP53LMNA | |
| SCHEMBL10243199 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ATP53LMNA | |
| SCHEMBL15214993 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ATP53LMNA | |
| SCHEMBL20772300 | 0.82 | TP53 (0.73) | ALDH1A1MEN1KMT2ATP53LMNA | |
| SCHEMBL14320884 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATP53LMNA | |
| SCHEMBL4518520 | 0.79 | MEN1 (0.57) | ALDH1A1MEN1KMT2ATP53LMNA | |
| SCHEMBL12189232 | 0.77 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2ATP53LMNA | |
| SCHEMBL12188938 | 0.76 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL27519960 | 0.76 | USP5 (0.60) | ALDH1A1MEN1KMT2ATP53LMNA | |
| SCHEMBL14321122 | 0.75 | SLC18A3 (0.46) | ALDH1A1MEN1KMT2ATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018868-A1 | SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEINS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-02-09 | — | — | WO | disclosed |