Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | USP5 | P45974 | 7/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10245136 | 0.93 | ALDH1A1 (0.59) | ALDH1A1TP53LMNAL3MBTL1HTT | |
| SCHEMBL15214993 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TP53LMNAL3MBTL1HTT | |
| SCHEMBL10243199 | 0.90 | ALDH1A1 (0.55) | ALDH1A1TP53LMNAL3MBTL1HTT | |
| SCHEMBL4518520 | 0.84 | MEN1 (0.57) | ALDH1A1TP53LMNAL3MBTL1HTT | |
| SCHEMBL12189232 | 0.83 | ALDH1A1 (0.72) | ALDH1A1TP53LMNAL3MBTL1HTT | |
| SCHEMBL12188938 | 0.82 | ALDH1A1 (0.70) | ALDH1A1LMNAL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL12646347 | 0.80 | USP2 (0.68) | ALDH1A1LMNAL3MBTL1HTTMEN1 | |
| SCHEMBL4480464 | 0.80 | ALDH1A1 (0.63) | ALDH1A1LMNAL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL12189227 | 0.79 | USP2 (0.71) | ALDH1A1LMNAL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL27519960 | 0.78 | USP5 (0.60) | ALDH1A1TP53LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130225621-A1 | SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEIN | UNIVERSITY OF TORONTO MISSISSAUGA (CA) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225621-A1 | SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEIN | STAT3, STAT1, STAT4 | ALDH1A1 4285/4885TP53 75/4885LMNA 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.