Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.54 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | CFTR | P13569 | 2/20 | 0.50 |
| ▸ | CTSC | P53634 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1392911 | 0.94 | LMNA (0.57) | IDH2LMNAMEN1KMT2ATDP1 | |
| SCHEMBL10245819 | 0.92 | IDH2 (0.55) | IDH2LMNAMEN1KMT2ATDP1 | |
| SCHEMBL1393153 | 0.92 | IDH2 (0.52) | IDH2LMNAMEN1KMT2ATDP1 | |
| SCHEMBL1391943 | 0.91 | LMNA (0.54) | IDH2LMNAMEN1KMT2ATDP1 | |
| SCHEMBL1392219 | 0.90 | LMNA (0.56) | IDH2LMNAMEN1KMT2ATDP1 | |
| SCHEMBL10245629 | 0.90 | LMNA (0.58) | IDH2LMNAMEN1KMT2ATDP1 | |
| SCHEMBL1391672 | 0.89 | IDH2 (0.74) | IDH2LMNAMEN1KMT2ATDP1 | |
| SCHEMBL1392585 | 0.89 | LMNA (0.52) | IDH2LMNAMEN1KMT2ATDP1 | |
| SCHEMBL10282877 | 0.89 | LMNA (0.52) | IDH2LMNAMEN1KMT2ATDP1 | |
| SCHEMBL1393160 | 0.89 | LMNA (0.55) | IDH2LMNAMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009151-A1 | Triazines And Related Compounds Having Antiviral Activity, Compositions And Methods Thereof | PROGENICS PHARMACEUTICALS, INC. (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120009151-A1 | Triazines And Related Compounds Having Antiviral Activity, Compositions And Methods Thereof | PROGENICS PHARMACEUTICALS, INC. (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009151-A1 | Triazines And Related Compounds Having Antiviral Activity, Compositions And Methods Thereof | HAVCR2, ZC3HAV1, MAVS | IDH2 1936/4885LMNA 3218/4885MEN1 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.