Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481193 | 0.92 | MAPT (0.53) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL481040 | 0.88 | SMN1; SMN2 (0.48) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL1755812 | 0.84 | MAPT (0.45) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL27705271 | 0.83 | MAPT (0.53) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL10246006 | 0.83 | CYP2C9 (0.46) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL31069853 | 0.82 | MAPT (0.72) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL481470 | 0.82 | CYSLTR1 (0.64) | CYSLTR1GRM2MRGPRX4CYSLTR2 | |
| SCHEMBL481620 | 0.82 | MAPT (0.48) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL10245928 | 0.81 | CYSLTR1 (0.44) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL481209 | 0.80 | MAPT (0.70) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817301-B1 | POTENTIATORS OF GLUTAMATE RECEPTORS | LILLY CO ELI (US) | 2012-02-01 | — | — | EP | disclosed |