Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | CPA2 | P48052 | 1/20 | 0.35 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10246348 | 0.84 | ALDH1A1 (0.40) | SIRT6SIRT1NMT2NMT1ALDH1A1 | |
| SCHEMBL24654168 | 0.80 | SIRT6 (0.48) | SIRT6SIRT1NMT2NMT1ALDH1A1 | |
| SCHEMBL21126096 | 0.79 | SIRT6 (0.49) | SIRT6SIRT1NMT2NMT1ALDH1A1 | |
| SCHEMBL25586502 | 0.76 | KMT2A (0.41) | ALDH1A1RECQLMAPK1MEN1KMT2A | |
| SCHEMBL14577009 | 0.75 | ALDH1A1 (0.46) | SIRT6SIRT1NMT2NMT1ALDH1A1 | |
| SCHEMBL14577008 | 0.75 | ALDH1A1 (0.46) | SIRT6SIRT1NMT2NMT1ALDH1A1 | |
| SCHEMBL14576862 | 0.75 | ALDH1A1 (0.46) | SIRT6SIRT1NMT2NMT1ALDH1A1 | |
| SCHEMBL14611679 | 0.74 | MAPT (0.45) | SIRT6SIRT1ALDH1A1TLR2KDM4E | |
| SCHEMBL14611729 | 0.74 | MAPT (0.45) | SIRT6SIRT1ALDH1A1TLR2KDM4E | |
| SCHEMBL14611821 | 0.74 | MAPT (0.45) | SIRT6SIRT1ALDH1A1TLR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012036907-A2 | BROAD SPECTRUM ANTIBIOTIC ARYLOMYCIN ANALOGS | ROMESBERG FLOYD E (US) | 2012-03-22 | — | — | WO | disclosed |