Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | PRSS12 | P56730 | 9/20 | 0.54 |
| ▸ | F10 | P00742 | 6/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733363 | 0.88 | PRSS12 (0.69) | PRSS12F10 | |
| SCHEMBL2721976 | 0.86 | PRSS12 (0.56) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL5540139 | 0.77 | PRSS12 (0.79) | PRSS12F10 | |
| SCHEMBL5542108 | 0.73 | PRSS12 (0.74) | PRSS12F10 | |
| SCHEMBL13212132 | 0.70 | MAPT (0.70) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL5534570 | 0.70 | PRSS12 (1.00) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL23353224 | 0.70 | MAPT (1.00) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL29865475 | 0.70 | MAPT (1.00) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL5935569 | 0.69 | MAPT (0.79) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL6594521 | 0.69 | F10 (1.00) | PRSS12F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059442-A2 | NEUROTRYPSIN INHIBITORS | NEUROTUNE AG (CH) | 2012-05-10 | — | — | WO | disclosed |