SCHEMBL1024658

SCHEMBL1024658

CC1CCC(C)NNN(C)CC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.32
PRMT6 Q96LA8 1/20 0.32
PRMT1 Q99873 1/20 0.32
PRMT8 Q9NR22 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24001039 0.86
SCHEMBL8003665 0.72 CYP1A2 (0.33)
SCHEMBL1660122 0.70 CARM1 (0.31) CARM1PRMT6PRMT1PRMT8
SCHEMBL14573053 0.67 CARM1 (0.44) CARM1PRMT6PRMT1PRMT8
SCHEMBL16491161 0.66
SCHEMBL1024659 0.65 NCF1 (0.43) CARM1PRMT6PRMT1PRMT8
SCHEMBL11641698 0.63
SCHEMBL11356031 0.61 CYP2C9 (0.59)
SCHEMBL13400 0.61
SCHEMBL20727002 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2708547-B1 Aqueous solutions of radiometal complexes with tridentate ligends UNIV ZUERICH (CH) 2018-06-20 EP claimed
EP-2274312-B1 METAL COMPLEXES UNIV ZUERICH (CH) 2015-06-03 EP claimed
EP-2708547-A1 AQUEOUS SOLUTIONS OF RADIOMETAL COMPLEXES WITH TRIDENTATE LIGENDS Universität Zürich (CH) 2014-03-19 EP claimed
US-20110065680-A1 Metal Complexes UNIVERSITY OF ZURICH (CH) 2011-03-17 US claimed
EP-2274312-A2 METAL COMPLEXES Universität Zürich (CH) 2011-01-19 EP claimed
WO-2009112823-A2 METAL COMPLEXES Universität Zürich (CH) 2009-09-17 WO claimed
US-7122711-B2 Method for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-17 US claimed
US-20030158419-A1 Method for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED 2003-08-21 US claimed
EP-1312605-A1 Method for producing biaryl compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-05-21 EP claimed
EP-2708547-B1 Aqueous solutions of radiometal complexes with tridentate ligends UNIV ZUERICH (CH) 2018-06-20 EP disclosed
EP-2274312-B1 METAL COMPLEXES UNIV ZUERICH (CH) 2015-06-03 EP disclosed
US-8961924-B2 Metal complexes UNIVERSITY OF ZURICH (CH) 2015-02-24 US disclosed
EP-2708547-A1 AQUEOUS SOLUTIONS OF RADIOMETAL COMPLEXES WITH TRIDENTATE LIGENDS Universität Zürich (CH) 2014-03-19 EP disclosed
EP-2708547-A1 AQUEOUS SOLUTIONS OF RADIOMETAL COMPLEXES WITH TRIDENTATE LIGENDS Universität Zürich (CH) 2014-03-19 EP disclosed
US-20110065680-A1 Metal Complexes UNIVERSITY OF ZURICH (CH) 2011-03-17 US disclosed
EP-2274312-A2 METAL COMPLEXES Universität Zürich (CH) 2011-01-19 EP disclosed
WO-2009112823-A2 METAL COMPLEXES Universität Zürich (CH) 2009-09-17 WO disclosed
US-7122711-B2 Method for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-17 US disclosed
US-20030158419-A1 Method for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED 2003-08-21 US disclosed
EP-1312605-A1 Method for producing biaryl compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-05-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030158419-A1 Method for producing biaryl compound B2M, BMI1, CYP2W1 CARM1 172/4885PRMT6 1077/4885PRMT1 621/4885
US-20110065680-A1 Metal Complexes CLTA, L3MBTL3, CLTB CARM1 3039/4885PRMT6 1331/4885PRMT1 1865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.