Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10246602 | 0.82 | — | — | |
| SCHEMBL7281285 | 0.80 | KDM4E (0.54) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL70060 | 0.80 | KDM4E (0.54) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL7229572 | 0.80 | KDM4E (0.54) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL16016389 | 0.79 | KDM4E (0.53) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL20327046 | 0.79 | KDM4E (0.53) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL11564268 | 0.78 | KDM4E (0.40) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL11561471 | 0.78 | KDM4E (0.40) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL12247553 | 0.78 | KDM4E (0.52) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL27339631 | 0.78 | HSD17B10 (0.58) | KDM4EHSD17B10ALOX15TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116014240-A | Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery using same | 三菱化学株式会社 | 2023-04-25 | — | — | CN | disclosed |
| WO-2022036123-A1 | METHODS AND COMPOSITIONS FOR TREATING POLYCYSTIC OVARY SYNDROME | SPRUCE BIOSCIENCES, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
| WO-2014100719-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |
| US-20120041193-A1 | SUBSTITUTED INTERNAL VINYL-BORONIC ACIDS AND BORONIC ACID DERIVATIVES | FRONTIER SCIENTIFIC, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| US-7928099-B2 | Pyrimido [4,5-D] azepine derivatives as 5-HT2c agonists | PFIZER INC (US) | 2011-04-19 | — | — | US | disclosed |
| US-20100113422-A1 | Pyrimido [4,5-D] Azepine Derivatives As 5-HT2C Agonists | ANDREWS MARK | 2010-05-06 | — | — | US | disclosed |
| EP-0079842-B1 | ACRYLIC COPOLYMERS BASED ON N-ACRYLYLPOLYMETHYLENE IMINES OR N-ACRYLYLDIALKYL AMIDES, N,N'-ACRYLYLDIAMINO ALCANES AND N-ACRYLYLAMINO ACIDS (OR ESTERS), THEIR PREPARATION AND THEIR USE AS CATION EXCHANGERS | Société d'Expansion Scientifique Expansia (FR) | 1985-08-14 | — | — | EP | disclosed |
| US-4526932-A | Copolymer containing N-coordinated triorganotin compound | NITTO KASEI CO., LTD. (JP) | 1985-07-02 | — | — | US | disclosed |
| EP-0079842-A1 | Acrylic copolymers based on N-acrylylpolymethylene imines or N-acrylyldialkyl amides, N,N'-acrylyldiamino alcanes and N-acrylylamino acids (or esters), their preparation and their use as cation exchangers | Société d'Expansion Scientifique Expansia (FR) | 1983-05-25 | — | — | EP | disclosed |
| US-4059581-A | Heterocyclic nitrogen containing siloxanes | UNION CARBIDE CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041193-A1 | SUBSTITUTED INTERNAL VINYL-BORONIC ACIDS AND BORONIC ACID DERIVATIVES | BLVRB, BTD, BCL6B | KDM4E 3155/4885HSD17B10 2088/4885ALOX15 2674/4885 |
| US-20100113422-A1 | Pyrimido [4,5-D] Azepine Derivatives As 5-HT2C Agonists | HTR2C, HTR2A, HTR5A | KDM4E 2290/4885HSD17B10 1813/4885ALOX15 1741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.