Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1755709 | 0.89 | MAPT (0.41) | GRM2CYSLTR1MAPTL3MBTL1CYP2C9 | |
| SCHEMBL1755775 | 0.87 | MAPT (0.41) | GRM2CYSLTR1MAPTL3MBTL1CYP2C9 | |
| SCHEMBL1755735 | 0.86 | CYSLTR1 (0.41) | GRM2CYSLTR1MAPTL3MBTL1CYP2C9 | |
| SCHEMBL1755713 | 0.86 | MAPT (0.40) | GRM2CYSLTR1MAPTL3MBTL1CYP2C9 | |
| SCHEMBL1755741 | 0.82 | MAPT (0.37) | GRM2CYSLTR1MAPTL3MBTL1CYP2C9 | |
| SCHEMBL481208 | 0.82 | LRRK2 (0.45) | GRM2CYSLTR1MAPTL3MBTL1CYP2C9 | |
| SCHEMBL481049 | 0.79 | GRM2 (0.64) | GRM2CYSLTR1MRGPRX4 | |
| SCHEMBL8263462 | 0.78 | CYSLTR1 (0.49) | GRM2CYSLTR1MAPTMEN1KMT2A | |
| SCHEMBL8263429 | 0.77 | GRM2 (0.44) | GRM2CYSLTR1MAPTL3MBTL1CYP2C9 | |
| Hydrochloric Acid SCHEMBL27831476 | 0.76 | MRGPRX4 (0.56) | GRM2CYSLTR1MAPTL3MBTL1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441762-A1 | Potentiators of Glutamate Receptors | Eli Lilly and Company (US) | 2012-04-18 | — | — | EP | disclosed |