Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481417 | 0.89 | MAPT (0.41) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL8264070 | 0.88 | MAPT (0.35) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL1755775 | 0.84 | MAPT (0.41) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL1755709 | 0.84 | MAPT (0.41) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL1755713 | 0.83 | MAPT (0.40) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL1755735 | 0.83 | CYSLTR1 (0.41) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL10247574 | 0.82 | GRM2 (0.42) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL481115 | 0.80 | CYSLTR1 (0.55) | CYSLTR1GRM2CYSLTR2 | |
| SCHEMBL1755806 | 0.79 | MAPT (0.35) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL1755738 | 0.77 | CYP2C9 (0.41) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441762-A1 | Potentiators of Glutamate Receptors | Eli Lilly and Company (US) | 2012-04-18 | — | — | EP | disclosed |