Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | BLM | P54132 | 2/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.71 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.71 |
| ▸ | DRD3 | P35462 | 1/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.71 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.71 |
| ▸ | EYA2 | O00167 | 1/20 | 0.67 |
| ▸ | APP | P05067 | 1/20 | 0.67 |
| ▸ | ACE | P12821 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15083253 | 0.98 | TDP1 (0.70) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL13863255 | 0.90 | TDP1 (0.58) | TDP1BLMPMP22KDM4EALOX15 | |
| Pentetic Acid SCHEMBL10564326 | 0.84 | TDP1 (1.00) | TDP1BLMPMP22KDM4EALOX15 | |
| Pentetic Acid SCHEMBL17138 | 0.84 | TDP1 (1.00) | TDP1BLMPMP22KDM4EALOX15 | |
| Pentetic Acid SCHEMBL2468143 | 0.84 | TDP1 (1.00) | TDP1BLMPMP22KDM4EALOX15 | |
| Pentetic Acid SCHEMBL786105 | 0.84 | TDP1 (1.00) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL8866720 | 0.84 | TDP1 (1.00) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL137691 | 0.84 | TDP1 (1.00) | TDP1BLMPMP22KDM4EALOX15 | |
| Pentetic Acid SCHEMBL8647927 | 0.82 | TDP1 (0.94) | TDP1BLMPMP22KDM4EALOX15 | |
| Pentetic Acid SCHEMBL9130818 | 0.82 | TDP1 (0.94) | TDP1BLMPMP22KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130136691-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2013-05-30 | — | — | US | disclosed |
| US-20130136691-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2013-05-30 | — | — | US | disclosed |
| US-8444954-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-05-21 | — | — | US | disclosed |
| US-8444954-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-05-21 | — | — | US | disclosed |
| US-8420053-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-04-16 | — | — | US | disclosed |
| US-8420053-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-04-16 | — | — | US | disclosed |
| US-8420050-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-04-16 | — | — | US | disclosed |
| US-8420050-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-04-16 | — | — | US | disclosed |
| US-8414864-B2 | Bombesin capable of complexing with metal ions, radionuclides, or optical labels; radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2013-04-09 | — | — | US | disclosed |
| US-8414864-B2 | Bombesin capable of complexing with metal ions, radionuclides, or optical labels; radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2013-04-09 | — | — | US | disclosed |
| EP-1583564-B1 | IMPROVED LINKERS FOR RADIOPHARMACEUTICAL COMPOUNDS | BRACCO IMAGING SPA (IT) | 2009-07-01 | — | — | EP | disclosed |
| US-20080247946-A1 | Bombesin capable of complexing with metal ions, radionuclides, or optical labels; radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2008-10-09 | — | — | US | disclosed |
| US-20080247946-A1 | Bombesin capable of complexing with metal ions, radionuclides, or optical labels; radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2008-10-09 | — | — | US | disclosed |
| US-20080008649-A1 | Gastrin Releasing Peptide Compounds | BRACCO IMAGING S.P.A. (IT) | 2008-01-10 | — | — | US | disclosed |
| US-20080008649-A1 | Gastrin Releasing Peptide Compounds | BRACCO IMAGING S.P.A. (IT) | 2008-01-10 | — | — | US | disclosed |
| US-20070231257-A1 | Radiodiagnosis, radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2007-10-04 | — | — | US | disclosed |
| US-20070231257-A1 | Radiodiagnosis, radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2007-10-04 | — | — | US | disclosed |
| US-7226577-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING, S. P. A. (IT) | 2007-06-05 | — | — | US | disclosed |
| US-7226577-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING, S. P. A. (IT) | 2007-06-05 | — | — | US | disclosed |
| WO-2007002500-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130136691-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | GRPR, GIPR, GHRHR | TDP1 3331/4885BLM 1481/4885PMP22 2560/4885 |
| US-20080008649-A1 | Gastrin Releasing Peptide Compounds | GRPR, SSTR5, GIPR | TDP1 4470/4885BLM 3914/4885PMP22 4702/4885 |
| US-20070231257-A1 | Radiodiagnosis, radiotherapy | GRPR, MRGPRX2, MRGPRX1 | TDP1 4460/4885BLM 3549/4885PMP22 1827/4885 |
| US-20080247946-A1 | Bombesin capable of complexing with metal ions, radionuclides, or optical labels; radiotherapy | GRPR, MRGPRX1, BRS3 | TDP1 4515/4885BLM 2500/4885PMP22 2794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.