Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140890 | 0.85 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL93561 | 0.84 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL2220386 | 0.83 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| Hydrogen Peroxide SCHEMBL28128571 | 0.83 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL4585244 | 0.82 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL18040479 | 0.81 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL16538074 | 0.81 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL221477 | 0.80 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL221202 | 0.80 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL21101830 | 0.80 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275841-B1 | Manufacturing method of hard coat liquid and plastic lens manufacturing method thereof. | HOYA CORP (JP) | 2014-12-10 | — | — | EP | disclosed |
| EP-2275841-A2 | Manufacturing method of hard coat liquid and plastic lens manufacturing method thereof | HOYA CORPORATION (JP) | 2011-01-19 | — | — | EP | disclosed |