SCHEMBL140890

SCHEMBL140890

C=CC(=O)OCCC[SiH2]C(OC)OC

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.53
ALDH1A1 P00352 4/20 0.53
CYP3A4 P08684 2/20 0.53
HPGD P15428 1/20 0.53
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
HSD17B10 Q99714 1/20 0.44
THRB P10828 2/20 0.38
ATM Q13315 1/20 0.35
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HCAR2 Q8TDS4 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16538074 0.95 TSHR (0.56) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29402140 0.94 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL26918864 0.94 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16537404 0.94 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL21101830 0.94 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL733860 0.90 TSHR (0.47) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1024881 0.85 TSHR (0.43) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL3914226 0.84 TSHR (0.47) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28135807 0.84 TSHR (0.42) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL394436 0.84 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025084741-A1 POLYOLEFIN GRAFT COPOLYMER PRODUCED USING INITIATOR CONTAINING AZIDOFORMATE GROUP AND PRODUCTION METHOD THEREFOR 세종대학교산학협력단 2025-04-24 WO claimed
US-11834429-B2 Monoethylenically unsaturated monomers and uses thereof BOSTIK SA (FR) 2023-12-05 US claimed
US-11814534-B2 Clay-polyacrylate composites suspension via in situ polymerization AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-11-14 US claimed
US-20230212417-A1 CLAY-POLYACRYLATE COMPOSITES SUSPENSION VIA IN SITU POLYMERIZATION AGENCY SCIENCE TECH & RES (SG) 2023-07-06 US claimed
US-20210179576-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF UNIVERSITE DE RENNES (FR) 2021-06-17 US claimed
EP-3802510-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF Bostik SA (FR) 2021-04-14 EP claimed
CN-112533910-A Monoethylenically unsaturated monomers and their use 博斯蒂克股份公司 2021-03-19 CN claimed
CN-106947031-B A kind of flucride siloxane fire retardant and the preparation method and application thereof 铨盛聚碳科技股份有限公司 2019-06-04 CN claimed
EP-1675880-B1 METHOD FOR PARTIAL OR TOTAL OXIDATION OF ONE OR SEVERAL THIOCARBONYLTHIO ENDS OF A POLYMER OBTAINED BY RADICAL POLYMERISATION CONTROLLED BY REVERSIBLE ADDITION-CLEAVAGE RHODIA CHIMIE SA (FR) 2019-03-13 EP claimed
WO-2018169490-A1 CLAY-POLYACRYLATE COMPOSITES SUSPENSION VIA IN SITU POLYMERIZATION AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-09-20 WO claimed
US-6512081-B1 Synthesis of dithioester chain transfer agents and use of bis(thioacyl) disulfides or dithioesters as chain transfer agents E.I. DUPONT NEMOURS AND COMPANY 2003-01-28 US claimed
WO-2002079305-A1 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION POLYMERAT PTY LTD (AU) 2002-10-10 WO claimed
US-6376615-B1 USING FREE RADICALS CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) 2002-04-23 US claimed
EP-1149075-A1 SYNTHESIS OF DITHIOESTER CHAIN TRANSFER AGENTS AND USE OF BIS(THIOACYL) DISULFIDES OR DITHIOESTERS AS CHAIN TRANSFER AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-10-31 EP claimed
US-6291620-B1 Polymer synthesis E. I. DU PONT DE NEMOURS AND COMPANY 2001-09-18 US claimed
US-6281297-B1 CONTAINING ALLYL METHACRYLATE AND ORGANOSILICON COMPOUND KANEKA CORPORATION (JP) 2001-08-28 US claimed
EP-0791016-B1 POLYMER SYNTHESIS DU PONT (US) 2000-07-12 EP claimed
WO-1999005099-A1 SYNTHESIS OF DITHIOESTER CHAIN TRANSFER AGENTS AND USE OF BIS(THIOACYL) DISULFIDES OR DITHIOESTERS AS CHAIN TRANSFER AGENTS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1999-02-04 WO claimed
EP-0791016-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-08-27 EP claimed
WO-1996015157-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-05-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834429-B2 Monoethylenically unsaturated monomers and uses thereof MEP1A, MEP1B, ALOX5 TSHR 4885/4885ALDH1A1 581/4885CYP3A4 1457/4885
US-20210179576-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF MEP1A, MEP1B, ALOX5 TSHR 4885/4885ALDH1A1 581/4885CYP3A4 1457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.