SCHEMBL1024887

SCHEMBL1024887

CC(Cl)N=C=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2134253 0.72
Isopropyl Isothiocyanate SCHEMBL213474 0.72
SCHEMBL28220625 0.69
Isopropyl Isothiocyanate SCHEMBL28808741 0.69
SCHEMBL11584330 0.67
SCHEMBL6658722 0.67
SCHEMBL11424714 0.67 TRPA1 (0.56)
SCHEMBL945811 0.67
SCHEMBL11576483 0.67
SCHEMBL7808164 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118496457-A Fluorine-containing degradable polymer and preparation method and application thereof 华南理工大学 2024-08-16 CN claimed
CN-115975159-A Squaramide ionic organic catalyst and synthesis method and application thereof 陕西榆能集团能源化工研究院有限公司 2023-04-18 CN claimed
CN-115073736-A Catalytic method for controllable copolymerization of epoxy and isothiocyanate 华南理工大学 2022-09-20 CN claimed
WO-2022188406-A1 CATALYTIC METHOD FOR CONTROLLABLE COPOLYMERIZATION OF EPOXY AND ISOTHIOCYANATE 华南理工大学 2022-09-15 WO claimed
CN-115073736-B Catalytic method for controllable copolymerization of epoxy and isothiocyanate 华南理工大学 2023-08-22 CN disclosed
CN-115975159-A Squaramide ionic organic catalyst and synthesis method and application thereof 陕西榆能集团能源化工研究院有限公司 2023-04-18 CN disclosed
CN-115073736-A Catalytic method for controllable copolymerization of epoxy and isothiocyanate 华南理工大学 2022-09-20 CN disclosed
WO-2022188406-A1 CATALYTIC METHOD FOR CONTROLLABLE COPOLYMERIZATION OF EPOXY AND ISOTHIOCYANATE 华南理工大学 2022-09-15 WO disclosed
US-20190091166-A1 BIOABSORBABLE SHEET OR FILM YOSHIDA YASUHIRO (JP) 2019-03-28 US disclosed
CN-109310795-A Bioabsorbable thin slice or film 吉田靖弘 2019-02-05 CN disclosed
EP-3427762-A1 BIOABSORBABLE SHEET OR FILM Yoshida, Yasuhiro (JP) 2019-01-16 EP disclosed
CN-107188866-A A kind of synthetic method of the ketone compounds of polysubstituted thiazole 4 湖北科技学院 2017-09-22 CN disclosed
US-5252595-A Method for reducing or maintaining intraocular pressure in the mammalian eye by administering pharmaceutical compositions containing 2-(2-alkylphenylamino)-oxazolines, 2-(2-alkylphenylamino)-thiazolines and 2-(2-alkylphenylamino)-imidazolines ALLERGAN, INC. (US) 1993-10-12 US disclosed
US-5151440-A Treatment of glaucoma ALLERGAN, INC. (US) 1992-09-29 US disclosed
US-5066664-A Control of intraocular bleeding and pressure ALLERGAN, INC. (US) 1991-11-19 US disclosed
US-4338315-A RHINOVIRUSES ELI LILLY AND COMPANY (US) 1982-07-06 US disclosed
US-4293558-A Antiviral thiazolinyl benzimidazoles and derivatives ELI LILLY AND COMPANY (US) 1981-10-06 US disclosed
US-4221798-A Hypotensive 2-heterocycloamino-imidazolines BEIERSDORF AKTIENGESELLSCHAFT (DE) 1980-09-09 US disclosed
US-4216313-A Antiviral thiazinyl benzimidazoles ELI LILLY AND COMPANY (US) 1980-08-05 US disclosed
US-4150028-A Antiviral thiazolinyl benzimidazoles ELI LILLY AND COMPANY (US) 1979-04-17 US disclosed