SCHEMBL10249583

SCHEMBL10249583

CC(C)(C)c1ccc(OC(=O)Oc2ccc(-c3ccc(OC(=O)Oc4ccc(C5(c6ccc(OC(=O)Oc7ccc(C(C)(C)C)cc7)cc6)CCCCC5)cc4)cc3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 1/20 0.49
▸ MAPT P10636 3/20 0.48
▸ RAB9A P51151 3/20 0.48
▸ SMN1; SMN2 Q16637 2/20 0.48
▸ NPC1 O15118 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ FAAH O00519 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ SLC6A2 P23975 1/20 0.39
▸ ESR1 P03372 2/20 0.39
▸ ESR2 Q92731 2/20 0.39
▸ HSD11B1 P28845 1/20 0.39
▸ NPSR1 Q6W5P4 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ TP53 P04637 2/20 0.37
▸ ALDH1A1 P00352 1/20 0.36
▸ THRB P10828 1/20 0.36
▸ LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17298988 0.96 ADORA3 (0.52) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL14357625 0.91 ADORA3 (0.48) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL16775316 0.91 ADORA3 (0.48) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL16405351 0.89 ADORA3 (0.49) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL19998369 0.88 ADORA3 (0.49) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL12242734 0.88 ELANE (0.49) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL20463358 0.87 ADORA3 (0.41) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL15887447 0.87 MAPT (0.45) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL17792236 0.85 MAPT (0.65) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL16576512 0.84 ADORA3 (0.43) ADORA3MAPTRAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180224760-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE INCLUDING THE SAME FUJI ELECTRIC CO., LTD. (JP) 2018-08-09 — — US disclosed
US-20180088475-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-03-29 — — US disclosed
US-9904186-B2 Electrophotographic photoreceptor, method for manufacturing same, and electrophotographic apparatus using same FUJI ELECTRIC CO., LTD. (JP) 2018-02-27 — — US disclosed
US-8927680-B2 Polycarbonate resin and coating solution containing same, and molded article produced by molding said coating solution IDEMITSU KOSAN CO., LTD. (JP) 2015-01-06 — — US disclosed
US-20140206814-A1 POLYCARBONATE RESIN AND COATING SOLUTION CONTAINING SAME, AND MOLDED ARTICLE PRODUCED BY MOLDING SAID COATING SOLUTION IDEMITSU KOSAN CO., LTD. (JP) 2014-07-24 — — US disclosed
US-8519082-B2 Polycarbonate copolymer, coating liquid using same, and electrophotographic photosensitive body IDEMITSU KOSAN CO., LTD. (JP) 2013-08-27 — — US disclosed
US-20120100474-A1 POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO., LTD. (JP) 2012-04-26 — — US disclosed
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