SCHEMBL17298988

SCHEMBL17298988

CC(C)(C)c1ccc(OC(=O)Oc2ccc(C3(c4ccc(OC(=O)Oc5ccc(C(C)(C)C)cc5)cc4)CCCCC3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 1/20 0.52
▸ MAPT P10636 4/20 0.51
▸ RAB9A P51151 3/20 0.51
▸ SMN1; SMN2 Q16637 2/20 0.51
▸ NPC1 O15118 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ FAAH O00519 1/20 0.44
▸ L3MBTL1 Q9Y468 2/20 0.44
▸ TDP1 Q9NUW8 2/20 0.44
▸ ESR1 P03372 2/20 0.42
▸ ESR2 Q92731 2/20 0.42
▸ NPSR1 Q6W5P4 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ TP53 P04637 2/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ THRB P10828 1/20 0.39
▸ LMNA P02545 2/20 0.38
▸ PRSS1 P07477 1/20 0.38
▸ ACR P10323 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10249583 0.96 ADORA3 (0.49) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL16775316 0.95 ADORA3 (0.48) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL14357625 0.95 ADORA3 (0.48) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL16405351 0.93 ADORA3 (0.49) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL19998369 0.92 ADORA3 (0.49) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL12242734 0.92 ELANE (0.49) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL17792236 0.89 MAPT (0.65) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL16576512 0.88 ADORA3 (0.43) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL15887455 0.88 ADORA3 (0.43) ADORA3MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL15887464 0.87 MAPT (0.50) ADORA3MAPTRAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180224760-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE INCLUDING THE SAME FUJI ELECTRIC CO., LTD. (JP) 2018-08-09 — — US disclosed
US-20180088475-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-03-29 — — US disclosed
US-9665019-B2 Electrophotographic photoconductor, production method thereof, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2017-05-30 — — US disclosed
US-20150346614-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PRODUCTION METHOD THEREOF, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2015-12-03 — — US disclosed
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