⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11303483 | 0.97 | DPP7 (0.39) | — | |
| SCHEMBL27137288 | 0.97 | DPP7 (0.39) | — | |
| SCHEMBL104446 | 0.97 | DPP7 (0.39) | — | |
| SCHEMBL27150404 | 0.97 | DPP7 (0.39) | — | |
| SCHEMBL11299622 | 0.97 | DPP7 (0.39) | — | |
| SCHEMBL27143448 | 0.94 | — | — | |
| SCHEMBL28175746 | 0.91 | DPP7 (0.31) | — | |
| SCHEMBL1792180 | 0.88 | — | — | |
| SCHEMBL29187652 | 0.88 | TSHR (0.33) | — | |
| SCHEMBL2130748 | 0.84 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574467-A | Polyamine-based compound and preparation method and application thereof | 江苏三月科技股份有限公司 | 2020-08-25 | — | — | CN | claimed |
| WO-2024043341-A1 | CYCLOALKYNE DERIVATIVE | ペプチドリーム株式会社 | 2024-02-29 | — | — | WO | disclosed |
| CN-111574467-B | Polyamine-based compound and preparation method and application thereof | 江苏三月科技股份有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-111574467-A | Polyamine-based compound and preparation method and application thereof | 江苏三月科技股份有限公司 | 2020-08-25 | — | — | CN | disclosed |
| US-9840567-B2 | Olefin polymerization process with continuous transfer | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2017-12-12 | — | — | US | disclosed |
| CN-107266893-A | High reflectance makrolon | 沙特基础全球技术有限公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-104220502-B | High-reflectivity polycarbonate | 沙特基础全球技术有限公司 | 2017-08-25 | — | — | CN | disclosed |
| US-9567416-B2 | Double loop technology | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2017-02-14 | — | — | US | disclosed |
| EP-2920214-B1 | OLEFIN POLYMERIZATION PROCESS WITH CONTINUOUS TRANSFER | TOTAL RES & TECHNOLOGY FELUY (BE) | 2016-04-27 | — | — | EP | disclosed |
| US-20160108149-A1 | Double Loop Technology | TOTAL RES & TECHNOLOGY FELUY (BE) | 2016-04-21 | — | — | US | disclosed |
| US-6696446-B1 | HETEROCYLCIC AMIDES SUCH AS N-(4-(3-(3-(3-ETHOXY-4-METHOXY PHENYL)-1,4,5,6-TETRAHYDRO-1-PYRIDAZINYLCARBONYL)PHENYLAMINO -CARBONYL)PHENYL)-4-NITROBENZAMIDE, SUED AS PHOSPHODIESTERASE INHIBITORSFOR PROPHYLAXIS OF ALLERGIES OR ASTHMA | MERCK PATENT GMBH (DE) | 2004-02-24 | — | — | US | disclosed |
| EP-1343769-A1 | BENZOYLPYRIDAZINES | MERCK PATENT GmbH (DE) | 2003-09-17 | — | — | EP | disclosed |
| WO-2003008373-A1 | TYROSINE HYDRAZIDES | MERCK PATENT GMBH (DE) | 2003-01-30 | — | — | WO | disclosed |
| WO-2003008392-A1 | 4-(BENZYLIDENE-AMINO)-3-(METHYLSULFANYL)-4H-(1, 2, 4) TRIAZIN-5-ONE DERIVATIVES HAVING A PDE-IV INHIBITING AND TNF-ANTAGONISTIC EFFECT FOR THE TREATMENT OF CARDIAC DISEASES AND ALLERGIES | MERCK PATENT GMBH (DE) | 2003-01-30 | — | — | WO | disclosed |
| US-6417188-B1 | ENZYME INHIBITORS OF PHOSPHODIESTERASE | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2002-07-09 | — | — | US | disclosed |
| WO-2002051814-A1 | BENZOYLPYRIDAZINES | MERCK PATENT GMBH (DE) | 2002-07-04 | — | — | WO | disclosed |
| EP-1194411-A1 | BENZOYLPYRIDAZINES | MERCK PATENT GmbH (DE) | 2002-04-10 | — | — | EP | disclosed |
| EP-1087946-A1 | ARYL ALKANOYLPYRIDAZINES | MERCK PATENT GmbH (DE) | 2001-04-04 | — | — | EP | disclosed |
| WO-2001004099-A1 | BENZOYLPYRIDAZINES | MERCK PATENT GMBH (DE) | 2001-01-18 | — | — | WO | disclosed |
| WO-1999065880-A1 | ARYL ALKANOYLPYRIDAZINES | MERCK PATENT GMBH (DE) | 1999-12-23 | — | — | WO | disclosed |