⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL880638 | 0.94 | MAPT (0.54) | — | |
| SCHEMBL378130 | 0.92 | MAPT (0.52) | — | |
| SCHEMBL11035687 | 0.92 | MAPT (0.52) | — | |
| SCHEMBL25821277 | 0.89 | HTT (0.48) | — | |
| SCHEMBL282864 | 0.88 | — | — | |
| SCHEMBL13902804 | 0.87 | HTR1A (0.52) | — | |
| SCHEMBL23384238 | 0.83 | CHRNA7 (0.46) | — | |
| SCHEMBL27324559 | 0.82 | KMT2A (0.43) | — | |
| SCHEMBL2919261 | 0.82 | MAPT (0.44) | — | |
| SCHEMBL2919264 | 0.80 | CA2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115835908-A | Bicyclic heterocycles as FGFR inhibitors | 因赛特公司 | 2023-03-21 | — | — | CN | claimed |
| CN-108473464-B | Isoindolinone inhibitors of MDM2-P53 interaction with anti-cancer activity | 阿斯泰克斯治疗有限公司 | 2022-08-23 | — | — | CN | claimed |
| CN-111343986-A | Compounds and pharmaceutical compositions thereof for the treatment of fibrotic diseases | 加拉帕戈斯股份有限公司 | 2020-06-26 | — | — | CN | claimed |
| CN-108473464-A | The isoindoline ketone inhibitors of MDM2-P53 interactions with active anticancer | 阿斯泰克斯治疗有限公司 | 2018-08-31 | — | — | CN | claimed |
| CN-103797011-B | As compound and the composition of c-Kit kinase inhibitor | NOVARTIS AG (CH) | 2016-03-30 | — | — | CN | claimed |
| CN-105120871-A | Use of pyrazolopyrimidine derivatives for the treatment of PI 3K-related disorders | INCYTE CORP | 2015-12-02 | — | — | CN | claimed |
| CN-103270036-B | As antiparasitic isoxazoline derivative | ZOETIS LLC (US) | 2015-11-25 | — | — | CN | claimed |
| CN-103159742-B | 5-chloropyrimide compounds and the application as EGFR tyrosine kinase inhibitor thereof | BEIJING HANMEI PHARMACEUTICAL CO., LTD. (CN) | 2015-08-12 | — | — | CN | claimed |
| CN-104024253-A | Heterocyclic amines as PI3K inhibitors | INCYTE CORP | 2014-09-03 | — | — | CN | claimed |
| CN-103270036-A | Isoxazoline derivatives as antiparasitic agents | PFIZER | 2013-08-28 | — | — | CN | claimed |
| CN-103159742-A | 5-Chloropyrimidine compound and application of 5-Chloropyrimidine compound serving as epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor | BEIJING HANMEI PHARMACEUTICAL CO LTD | 2013-06-19 | — | — | CN | claimed |
| WO-2010049731-A1 | PYRAZOLO- AND IMIDAZOPYRIDINYLPYRIMIDINEAMINES AS IGF-1R TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-05-06 | — | — | WO | claimed |
| US-6992115-B2 | Preparation of crosslinked particles from polymers having activatible crosslinking groups | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2006-01-31 | — | — | US | claimed |
| US-20050202338-A1 | PREPARATION OF CROSSLINKED PARTICLES FROM POLYMERS HAVING ACTIVATIBLE CROSSLINKING GROUPS | HAWKER CRAIG J (US) | 2005-09-15 | — | — | US | claimed |
| US-20030168251-A1 | Preparation of crosslinked particles from polymers having activatible crosslinking groups | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2003-09-11 | — | — | US | claimed |
| EP-4288426-B1 | QUINOXALINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS INC (US) | 2026-02-04 | — | — | EP | disclosed |
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| US-20050202338-A1 | PREPARATION OF CROSSLINKED PARTICLES FROM POLYMERS HAVING ACTIVATIBLE CROSSLINKING GROUPS | HAWKER CRAIG J (US) | 2005-09-15 | — | — | US | disclosed |
| US-6890703-B2 | Preparation of crosslinked particles from polymers having activatible crosslinking groups | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2005-05-10 | — | — | US | disclosed |
| US-20030168251-A1 | Preparation of crosslinked particles from polymers having activatible crosslinking groups | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2003-09-11 | — | — | US | disclosed |