Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1022496 | 1.00 | PRCP (0.47) | PRCPPNMTMEN1KMT2AFABP7 | |
| SCHEMBL1564243 | 1.00 | PRCP (0.47) | PRCPPNMTMEN1KMT2AFABP7 | |
| Hydrochloric Acid SCHEMBL8078996 | 0.98 | PRCP (0.46) | PRCPPNMTMEN1KMT2AFABP7 | |
| SCHEMBL9408124 | 0.90 | GAA (0.48) | PRCPPNMTMEN1KMT2AGAA | |
| SCHEMBL6298781 | 0.85 | PRCP (0.42) | PRCPPNMTMEN1KMT2A | |
| SCHEMBL27472422 | 0.85 | PRCP (0.42) | PRCPPNMTMEN1KMT2A | |
| SCHEMBL6010092 | 0.82 | PRCP (0.44) | PRCPPNMTMEN1KMT2A | |
| SCHEMBL6010348 | 0.82 | PRCP (0.44) | PRCPPNMTMEN1KMT2A | |
| SCHEMBL13940779 | 0.82 | MEN1 (0.44) | PRCPPNMTMEN1KMT2A | |
| SCHEMBL9548218 | 0.81 | DRD2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836485-B1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2018-01-10 | — | — | EP | claimed |
| EP-2462147-B1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2014-11-12 | — | — | EP | claimed |
| EP-1227803-B1 | COMPOUNDS FOR INHIBITING IAPP-ASSOCIATED AMYLOID DEPOSITS | BELLUS HEALTH INTERNATIONAL LTD (CH) | 2010-05-05 | — | — | EP | claimed |
| EP-0751128-B2 | Process for producing optically active amides | AJINOMOTO KK (JP) | 2005-08-31 | — | — | EP | claimed |
| EP-1104755-B1 | Process for the preparation of (S)-N-tertbutyl-1,2,3,4- tetrahydroisoquinoline-3-carboxamide | CLARIANT LSM ITALIA SPA (IT) | 2004-10-06 | — | — | EP | claimed |
| EP-0902781-B1 | PREPARATION OF (S)-DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID T-BUTYLAMIDE | PCBU SERVICES INC (US) | 2003-12-17 | — | — | EP | claimed |
| EP-1009749-B1 | PREPARATION OF (S)-N-TERT-BUTYL-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYAMIDE | CLARIANT LSM ITALIA SPA (IT) | 2001-08-08 | — | — | EP | claimed |
| EP-0751128-B1 | Process for producing optically active amides | AJINOMOTO KK (JP) | 1999-07-28 | — | — | EP | claimed |
| EP-1682513-B1 | METHOD FOR PRODUCING CYCLIC, N-SUBSTITUTED ALPHA-IMINOCARBOXYLIC ACIDS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-01-12 | — | — | EP | disclosed |
| EP-0432694-B1 | Aminoalcohols | HOFFMANN LA ROCHE (CH) | 1996-05-29 | — | — | EP | disclosed |
| EP-0657419-A1 | Alcohols | F. HOFFMANN-LA ROCHE AG (CH) | 1995-06-14 | — | — | EP | disclosed |
| EP-0532466-A2 | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |
| EP-0432694-A2 | Aminoalcohols | F. HOFFMANN-LA ROCHE AG (CH) | 1991-06-19 | — | — | EP | disclosed |