Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6010092 | 1.00 | PRCP (0.44) | PRCPPNMTOPRM1OPRD1OPRK1 | |
| SCHEMBL6298781 | 0.84 | PRCP (0.42) | PRCPPNMTMEN1KMT2A | |
| SCHEMBL27472422 | 0.84 | PRCP (0.42) | PRCPPNMTMEN1KMT2A | |
| SCHEMBL17866218 | 0.84 | PNMT (0.40) | PNMT | |
| SCHEMBL1564243 | 0.82 | PRCP (0.47) | PRCPPNMTMEN1KMT2A | |
| SCHEMBL1022496 | 0.82 | PRCP (0.47) | PRCPPNMTMEN1KMT2A | |
| SCHEMBL1025366 | 0.82 | PRCP (0.47) | PRCPPNMTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8078996 | 0.81 | PRCP (0.46) | PRCPPNMTMEN1KMT2A | |
| SCHEMBL7827898 | 0.80 | PNMT (0.39) | PRCPPNMTMEN1KMT2A | |
| SCHEMBL9021927 | 0.79 | KMT2A (0.43) | PRCPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861236-B2 | CYCLIC AND HETEROCYCLIC N-SUBSTITUTED ALPHA-IMINOHYDROXAMIC AND CARBOXYLIC ACIDS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-08-16 | — | — | EP | disclosed |
| EP-0861236-B1 | CYCLIC AND HETEROCYCLIC N-SUBSTITUTED ALPHA-IMINOHYDROXAMIC AND CARBOXYLIC ACIDS | HOECHST AG (DE) | 2002-02-13 | — | — | EP | disclosed |
| EP-0578163-A1 | Process for the preparation of D,L or D,L-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-12 | — | — | EP | disclosed |
| EP-0511347-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | Pentapharm A.G. (CH) | 1992-11-04 | — | — | EP | disclosed |
| WO-1992016549-A1 | PARASUBSTITUTED PHENYLALANINE DERIVATES | PENTAPHARM AG (CH) | 1992-10-01 | — | — | WO | disclosed |
| WO-1992008709-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | PENTAPHARM AG (CH) | 1992-05-29 | — | — | WO | disclosed |