⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475059 | 1.00 | — | — | |
| SCHEMBL31518161 | 1.00 | — | — | |
| SCHEMBL6673550 | 1.00 | — | — | |
| SCHEMBL258635 | 1.00 | — | — | |
| SCHEMBL9295522 | 1.00 | — | — | |
| SCHEMBL8542060 | 1.00 | — | — | |
| SCHEMBL10754844 | 0.96 | CCR5 (0.53) | — | |
| SCHEMBL21440674 | 0.96 | CCR5 (0.53) | — | |
| SCHEMBL18155356 | 0.96 | CCR5 (0.53) | — | |
| SCHEMBL21349622 | 0.96 | CCR5 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022096-A1 | NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | GENECODE (EE) | 2026-01-22 | — | — | US | claimed |
| CN-119959406-A | Method for detecting cis-all-hydrogen isoindole and trans-isomer in salt thereof | 北京四环科宝制药股份有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-118772029-A | Anti-atopic dermatitis active enaminones compound, preparation and application thereof | 中国医学科学院药物研究所 | 2024-10-15 | — | — | CN | claimed |
| CN-114890933-B | Preparation method of racemic mitiglinide | 恒升德康(南京)医药科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-115894332-A | Preparation method of mitiglinide calcium intermediate | 北京四环科宝制药股份有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-114890933-A | Preparation method of racemic mitiglinide | 恒升德康(南京)医药科技有限公司 | 2022-08-12 | — | — | CN | claimed |
| CN-108752260-B | Preparation method of mitiglinide calcium intermediate | 江西济民可信药业有限公司 | 2021-07-27 | — | — | CN | claimed |
| CN-108982706-B | Method for detecting impurity cis-perhydroisoindole in mitiglinide calcium | 山东铂源药业有限公司 | 2021-03-02 | — | — | CN | claimed |
| CN-110256328-A | A kind of preparation method of R- Mitiglinide Calcium | 江西济民可信药业有限公司 | 2019-09-20 | — | — | CN | claimed |
| CN-108982706-A | The detection method of impurity cis-hexahydroisoindoline in a kind of Mitiglinide Calcium | 山东铂源药业有限公司 | 2018-12-11 | — | — | CN | claimed |
| CN-100506794-C | New method for preparing medicine mitiglinide for treating diabetes | SHANGHAI INST MATERIA MEDICA (CN) | 2009-07-01 | — | — | CN | claimed |
| WO-2009047797-A2 | PROCESS FOR THE PREPARATION OF PERHYDROISOINDOLE DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2009-04-16 | — | — | WO | claimed |
| CN-101381338-A | Method for preparing cis-hexahydroisoindoline | SHANGHAI INST PHARM INDUSTRY (CN) | 2009-03-11 | — | — | CN | claimed |
| WO-2005049589-A2 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA, DIABETES, OBESITY AND SIMILAR DISEASES | CADILA HEALTHCARE LIMITED (IN) | 2005-06-02 | — | — | WO | claimed |
| CN-1616427-A | New method for preparing medicine mitiglinide for treating diabetes | SHANGHAI INST MATERIA MEDICA (CN) | 2005-05-18 | — | — | CN | claimed |
| WO-2005030719-A1 | NOVEL METHOD FOR PREPARING CIS-OCTAHYDRO-ISOINDOLE | LES LABORATOIRES SERVIER (FR) | 2005-04-07 | — | — | WO | claimed |
| WO-2005030718-A1 | NOVEL METHOD OF PREPARING CIS-OCTAHYDRO-ISOINDOLE | LES LABORATOIRES SERVIER (FR) | 2005-04-07 | — | — | WO | claimed |
| EP-0899259-B1 | Process for the preparation of cis-hexahydroisoindolines | YUKI GOSEI YAKUHIN KOGYO KK (JP) | 2004-10-13 | — | — | EP | claimed |
| US-5932744-A | Process for the preparation of cis-hexahydroisoindoline derivatives | YUKI GOSEI KOGYO CO., LTD. (JP) | 1999-08-03 | — | — | US | claimed |
| EP-0899259-A1 | Process for the preparation of cis-hexahydroisoindolines | YUKI GOSEI KOGYO CO., LTD. (JP) | 1999-03-03 | — | — | EP | claimed |