⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475059 | 1.00 | — | — | |
| SCHEMBL1025624 | 1.00 | — | — | |
| SCHEMBL31518161 | 1.00 | — | — | |
| SCHEMBL258635 | 1.00 | — | — | |
| SCHEMBL9295522 | 1.00 | — | — | |
| SCHEMBL8542060 | 1.00 | — | — | |
| SCHEMBL10754844 | 0.96 | CCR5 (0.53) | — | |
| SCHEMBL21440674 | 0.96 | CCR5 (0.53) | — | |
| SCHEMBL18155356 | 0.96 | CCR5 (0.53) | — | |
| SCHEMBL21349622 | 0.96 | CCR5 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214570-A2 | N-alkylated tripeptides, process for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-18 | — | — | EP | claimed |
| US-10981887-B2 | Benzothiophene estrogen receptor modulators | G1 THERAPEUTICS, INC. (US) | 2021-04-20 | — | — | US | disclosed |
| US-20200216406-A1 | BENZOTHIOPHENE ESTROGEN RECEPTOR MODULATORS | G1 THERAPEUTICS, INC. (US) | 2020-07-09 | — | — | US | disclosed |
| US-10633362-B2 | Benzothiophene estrogen receptor modulators | G1 THERAPEUTICS, INC. (US) | 2020-04-28 | — | — | US | disclosed |
| US-20190119243-A1 | BENZOTHIOPHENE ESTROGEN RECEPTOR MODULATORS | G1 THERAPEUTICS, INC. (US) | 2019-04-25 | — | — | US | disclosed |
| US-10208011-B2 | Benzothiophene estrogen receptor modulators | G1 THERAPEUTICS, INC. (US) | 2019-02-19 | — | — | US | disclosed |
| CN-1741993-A | Process for producing cyclic amines | NEW JAPAN CHEM CO LTD (JP) | 2006-03-01 | — | — | CN | disclosed |
| EP-0899259-B1 | Process for the preparation of cis-hexahydroisoindolines | YUKI GOSEI YAKUHIN KOGYO KK (JP) | 2004-10-13 | — | — | EP | disclosed |
| WO-2004048327-A1 | PROCESS FOR PRODUCING CYCLIC AMINE | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2004-06-10 | — | — | WO | disclosed |
| US-5932744-A | Process for the preparation of cis-hexahydroisoindoline derivatives | YUKI GOSEI KOGYO CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0899259-A1 | Process for the preparation of cis-hexahydroisoindolines | YUKI GOSEI KOGYO CO., LTD. (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |
| US-4691022-A | Process for the preparation of monocyclic, bicyclic and tricyclic aminoacids | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-01 | — | — | US | disclosed |
| EP-0132580-A1 | Process for the preparation of mono, bi and tricyclic aminoacids | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-02-13 | — | — | EP | disclosed |