Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025827 | 0.84 | PTPN11 (0.44) | RARBKMT2ARXRA | |
| SCHEMBL1021907 | 0.82 | RARB (0.51) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL1021908 | 0.82 | RARB (0.51) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL1022110 | 0.81 | PTGS1 (0.46) | ALDH1A1PTGS1 | |
| SCHEMBL1023950 | 0.79 | PTPN1 (0.42) | PTGS1 | |
| SCHEMBL1024053 | 0.77 | PTGS2 (0.54) | PTGS1 | |
| SCHEMBL1020565 | 0.77 | PTGS1 (0.44) | ALDH1A1MAPTPTGS1 | |
| SCHEMBL1021200 | 0.76 | PTGS1 (0.31) | PTGS1 | |
| SCHEMBL1022880 | 0.75 | BRD4 (0.39) | RARBALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL1021572 | 0.74 | PTGS2 (0.38) | MEN1MAPTKMT2ATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841729-B1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORP (KR) | 2011-01-12 | — | — | EP | claimed |