Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1022157 | 0.88 | PTGS2 (0.51) | PTGS2PTGS1HSD17B1PDE5APGR | |
| SCHEMBL1022350 | 0.85 | PTGS2 (0.49) | PTGS2PTGS1HSD17B1PDE5APGR | |
| SCHEMBL1021324 | 0.84 | PTGS2 (0.48) | PTGS2PTGS1HSD17B1PDE5APGR | |
| SCHEMBL1021420 | 0.83 | PTGS2 (0.50) | PTGS2PTGS1HSD17B1PDE5APGR | |
| SCHEMBL1022376 | 0.81 | PTGS1 (0.50) | PTGS2PTGS1 | |
| SCHEMBL1020926 | 0.78 | PTGS2 (0.57) | PTGS2PTGS1HSD17B1PGR | |
| SCHEMBL1021461 | 0.77 | PTGS2 (0.35) | PTGS2PTGS1 | |
| SCHEMBL1021462 | 0.77 | PTGS2 (0.35) | PTGS2PTGS1 | |
| SCHEMBL1022426 | 0.73 | HSD17B1 (0.47) | PTGS2PTGS1HSD17B1 | |
| SCHEMBL1023688 | 0.72 | PTGS2 (0.51) | PTGS2PTGS1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841729-B1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORP (KR) | 2011-01-12 | — | — | EP | claimed |