Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | USP19 | O94966 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472907 | 0.92 | GFER (0.46) | GFERNAAAUSP19FFAR1FFAR4 | |
| SCHEMBL14327376 | 0.92 | FFAR1 (0.39) | USP19FFAR1FFAR4EPHX2CHRNB2 | |
| SCHEMBL13183012 | 0.86 | NAAA (0.48) | NAAAFFAR1FFAR4CHRNB2CHRNB4 | |
| SCHEMBL12195035 | 0.84 | GFER (0.46) | GFERNAAAEPHX2GPR183KMT2A | |
| SCHEMBL14312423 | 0.83 | GFER (0.43) | GFERNAAAUSP19FFAR1FFAR4 | |
| SCHEMBL13183026 | 0.82 | GFER (0.44) | GFERUSP19EPHX2GPR183KMT2A | |
| SCHEMBL14327389 | 0.81 | METAP2 (0.46) | GFERUSP19FFAR1EPHX2GPR183 | |
| SCHEMBL2513258 | 0.80 | MEN1 (0.50) | GFERFFAR1EPHX2GPR183KMT2A | |
| SCHEMBL2471516 | 0.80 | OPRL1 (0.56) | GFERNAAAEPHX2GPR183KMT2A | |
| SCHEMBL2467659 | 0.79 | OPRL1 (0.57) | GFEREPHX2GPR183KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501467-B1 | HETEROCYCLO INHIBITORS OF POTASSIUM CHANNEL FUNCTION | BRISTOL MYERS SQUIBB CO (US) | 2012-05-09 | — | — | EP | disclosed |