SCHEMBL1025905

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1025021	0.89	TMPRSS4 (0.57)	P2RX1TMPRSS4KCNMA1STIM1ORAI1
	SCHEMBL12773795	0.88	PPARG (0.46)	P2RX1STIM1ORAI1TRPC1TRPC3
	SCHEMBL1027295	0.84	PLG (0.43)	P2RX1KCNMA1PLGKLK1KLK6
	SCHEMBL1023055	0.78	MEN1 (0.55)	P2RX1TMPRSS4KCNMA1MEN1KMT2A
	SCHEMBL1367403	0.78	HTT (0.57)	KCNMA1MEN1KMT2AHDAC1NPC1
	SCHEMBL1024652	0.78	MEN1 (0.57)	P2RX1TMPRSS4KCNMA1MEN1KMT2A
	SCHEMBL1025872	0.77	MEN1 (0.56)	P2RX1TMPRSS4KCNMA1MEN1KMT2A
	SCHEMBL1024009	0.76	MEN1 (0.55)	P2RX1TMPRSS4KCNMA1MEN1KMT2A
	SCHEMBL1027417	0.76	TMPRSS4 (0.56)	P2RX1TMPRSS4KCNMA1MEN1KMT2A
	SCHEMBL1025816	0.76	P2RX1 (0.51)	P2RX1TMPRSS4STIM1ORAI1TRPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.