SCHEMBL1025909

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1026576	0.91	KCNMA1 (0.47)	KCNMA1P2RX1TMPRSS4JAK2JAK1
	SCHEMBL1027417	0.91	TMPRSS4 (0.56)	KCNMA1P2RX1TMPRSS4JAK2JAK1
	SCHEMBL1025840	0.81	KCNMA1 (0.62)	KCNMA1MEN1KMT2AHDAC1
	SCHEMBL1028260	0.81	KCNMA1 (0.43)	KCNMA1P2RX1JAK2JAK1TYK2
	SCHEMBL1024530	0.81	P2RX1 (0.47)	KCNMA1P2RX1JAK2TYK2KMT2A
	SCHEMBL1026305	0.79	KDM4E (0.48)	KCNMA1P2RX1TMPRSS4JAK2JAK1
	SCHEMBL1025723	0.79	KDM4E (0.51)	KCNMA1P2RX1TMPRSS4JAK2JAK1
	SCHEMBL1024652	0.78	MEN1 (0.57)	KCNMA1P2RX1TMPRSS4JAK2JAK1
	SCHEMBL1027316	0.78	P2RX1 (0.50)	P2RX1TMPRSS4JAK2JAK1TYK2
	SCHEMBL12776121	0.78	JAK2 (0.53)	P2RX1TMPRSS4JAK2JAK1TYK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.