Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 16/20 | 0.54 |
| ▸ | HTR1F | P30939 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4506328 | 0.99 | GPR6 (0.53) | GPR6HTR1FKMT2A | |
| SCHEMBL4504390 | 0.90 | HTR1F (0.49) | GPR6HTR1FKMT2A | |
| SCHEMBL4506654 | 0.88 | HTR1F (0.53) | GPR6HTR1FKMT2A | |
| SCHEMBL4493318 | 0.85 | ALDH1A1 (0.47) | GPR6HTR1FKMT2A | |
| SCHEMBL4503794 | 0.85 | HTR1F (0.49) | GPR6HTR1FKMT2A | |
| SCHEMBL10259733 | 0.83 | HTR1F (0.51) | GPR6HTR1FKMT2A | |
| SCHEMBL4494292 | 0.83 | HTR1F (0.53) | HTR1FKMT2A | |
| SCHEMBL4504844 | 0.83 | HTR1F (0.53) | GPR6HTR1FKMT2A | |
| Hydrochloric Acid SCHEMBL4514308 | 0.82 | HTR1F (0.50) | GPR6HTR1FKMT2A | |
| SCHEMBL10261060 | 0.82 | GSK3B (0.56) | HTR1FKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626958-B1 | (PIPERIDINYLOXY)PHENYL, (PIPERIDINYLOXY)PYRIDINYL, (PIPERIDINYLSULFANYL)PHENYL AND (PIPERIDINYLSULFANYL)PYRIDINYL COMPOUNDS AS 5-HT 1F AGONISTS | LILLY CO ELI (US) | 2012-06-27 | — | — | EP | disclosed |
| US-7608629-B2 | (Piperidinyloxy)phenyl, (piperidinyloxy)pyridinyl, (piperidinylsulfanyl)phenyl and (piperidinylsulfanyl)pyridinyl compounds as 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 2009-10-27 | — | — | US | disclosed |
| US-7608629-B2 | (Piperidinyloxy)phenyl, (piperidinyloxy)pyridinyl, (piperidinylsulfanyl)phenyl and (piperidinylsulfanyl)pyridinyl compounds as 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 2009-10-27 | — | — | US | disclosed |