Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4517763 | 0.99 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2MAPK7EGFR | |
| SCHEMBL10260259 | 0.96 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2MAPK7HTR1F | |
| Hydrochloric Acid SCHEMBL4508333 | 0.95 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2MAPK7HTR1F | |
| SCHEMBL10267808 | 0.92 | HTR1F (0.53) | MAPK7HTR1FSLC2A1RORCSLC5A7 | |
| Hydrochloric Acid SCHEMBL4509359 | 0.91 | HTR1F (0.52) | MAPK7HTR1FSLC2A1RORCSLC5A7 | |
| SCHEMBL4492648 | 0.88 | MAPT (0.53) | RAB9ANPC1SMN1; SMN2MAPK7HTR1F | |
| SCHEMBL10261919 | 0.84 | HTR1F (0.54) | RAB9ANPC1MAPK7HTR1F | |
| SCHEMBL10267494 | 0.83 | GRM4 (0.51) | RAB9ANPC1SMN1; SMN2SLC2A1GRM4 | |
| Hydrochloric Acid SCHEMBL4506091 | 0.83 | HTR1F (0.53) | RAB9ANPC1MAPK7HTR1F | |
| SCHEMBL13674973 | 0.83 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2HTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626958-B1 | (PIPERIDINYLOXY)PHENYL, (PIPERIDINYLOXY)PYRIDINYL, (PIPERIDINYLSULFANYL)PHENYL AND (PIPERIDINYLSULFANYL)PYRIDINYL COMPOUNDS AS 5-HT 1F AGONISTS | LILLY CO ELI (US) | 2012-06-27 | — | — | EP | disclosed |
| US-7608629-B2 | (Piperidinyloxy)phenyl, (piperidinyloxy)pyridinyl, (piperidinylsulfanyl)phenyl and (piperidinylsulfanyl)pyridinyl compounds as 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 2009-10-27 | — | — | US | disclosed |
| US-7608629-B2 | (Piperidinyloxy)phenyl, (piperidinyloxy)pyridinyl, (piperidinylsulfanyl)phenyl and (piperidinylsulfanyl)pyridinyl compounds as 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 2009-10-27 | — | — | US | disclosed |