Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CLPP | Q16740 | 2/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749624 | 1.00 | CYP3A4 (0.43) | CYP3A4ALDH1A1APOBEC3AAPOBEC3GMEN1 | |
| SCHEMBL746731 | 0.93 | CYP3A4 (0.43) | CYP3A4ALDH1A1APOBEC3AAPOBEC3GMEN1 | |
| SCHEMBL749613 | 0.93 | CYP3A4 (0.44) | CYP3A4ALDH1A1APOBEC3AAPOBEC3GMEN1 | |
| SCHEMBL747387 | 0.93 | CLPP (0.43) | CYP3A4ALDH1A1POLBCLPP | |
| SCHEMBL749671 | 0.91 | PKM (0.42) | CYP3A4ALDH1A1APOBEC3AAPOBEC3GMEN1 | |
| SCHEMBL745982 | 0.91 | CYP3A4 (0.38) | CYP3A4LMNASMN1; SMN2CLPP | |
| SCHEMBL749607 | 0.91 | CLPP (0.46) | CYP3A4ALDH1A1APOBEC3AAPOBEC3GSMN1; SMN2 | |
| SCHEMBL750691 | 0.91 | CYP3A4 (0.52) | CYP3A4CLPP | |
| SCHEMBL749577 | 0.90 | CYP3A4 (0.46) | CYP3A4MEN1KMT2ACLPPCACNA1G | |
| SCHEMBL745988 | 0.90 | MEN1 (0.49) | CYP3A4MEN1KMT2ACLPPCACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101751-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-01-24 | — | — | US | disclosed |
| US-8101751-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-01-24 | — | — | US | disclosed |