Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28303509 | 0.97 | KCNN4 (0.43) | KCNN4ALDH1A1TSHRMAPK1CYP1A2 | |
| Bromide SCHEMBL28212776 | 0.97 | KCNN4 (0.43) | KCNN4ALDH1A1TSHRMAPK1CYP1A2 | |
| Bromide SCHEMBL28212775 | 0.97 | KCNN4 (0.43) | KCNN4ALDH1A1TSHRMAPK1CYP1A2 | |
| Bromide SCHEMBL27870891 | 0.97 | KCNN4 (0.43) | KCNN4ALDH1A1TSHRMAPK1CYP1A2 | |
| SCHEMBL416260 | 0.97 | KCNN4 (0.47) | KCNN4ALDH1A1TSHRMAPK1CYP1A2 | |
| Hydrochloric Acid SCHEMBL28904471 | 0.93 | KCNN4 (0.45) | KCNN4ALDH1A1TSHRMAPK1CYP1A2 | |
| Hydrochloric Acid SCHEMBL28904470 | 0.93 | KCNN4 (0.45) | KCNN4ALDH1A1TSHRMAPK1CYP1A2 | |
| Iodide SCHEMBL114296 | 0.93 | KCNN4 (0.45) | KCNN4ALDH1A1TSHRMAPK1CYP1A2 | |
| SCHEMBL30581193 | 0.93 | KCNN4 (0.45) | KCNN4ALDH1A1TSHRMAPK1CYP1A2 | |
| Hydrochloric Acid SCHEMBL113885 | 0.93 | KCNN4 (0.45) | KCNN4ALDH1A1TSHRMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079956-A | Preparation method of heterocyclic compound | — | 2026-05-26 | — | — | CN | claimed |
| CN-119978028-A | Preparation method of high-temperature-resistant phosphorus salt antistatic agent | 达创新材料科技(山东)有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119613346-A | Method for preparing 5-bromopyrimidine | 上海沃缨生物科技有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119219648-A | Preparation method of (1S) -1- (hydroxymethyl) -2-oxa-5-azabicyclo [2.2.1] heptane-5-carboxylic acid tert-butyl ester | 浙江药领医药科技有限公司 | 2024-12-31 | — | — | CN | claimed |
| CN-118932196-A | Method for separating rhenium and molybdenum by utilizing quaternary phosphonium salt modified material | 武汉轻工大学 | 2024-11-12 | — | — | CN | claimed |
| CN-114835563-B | Synthesis method of 4,4' -difluorobenzophenone | 浙江中欣氟材股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117024263-A | Preparation method of 2,4, 6-trifluoro-benzoic acid | 黑龙江立科新材料有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-116813529-A | Synthesis method of 6-tert-butoxycarbonyl-2-amino-6-azaspiro [3.4] octane | 安顺市人民医院 | 2023-09-29 | — | — | CN | claimed |
| CN-114425304-B | Molecular sieve immobilized eutectic solvent material and preparation and application thereof | 中国石油化工股份有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-115819362-A | Efficient triallyl isocyanurate production process | 北京华和拓科技开发有限责任公司 | 2023-03-21 | — | — | CN | claimed |
| WO-2007101769-A1 | PROCESS FOR THE HYDROGENATION OF IMINES | EVONIK DEGUSSA GMBH (DE) | 2007-09-13 | — | — | WO | claimed |
| US-20070213540-A1 | Process for the hydrogenation of imines | DEGUSSA AG (DE) | 2007-09-13 | — | — | US | claimed |
| EP-1663999-A2 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES, LTD. (IN) | 2006-06-07 | — | — | EP | claimed |
| US-20050075383-A1 | Inhibitors of phophodiesterase type-IV | RANBAXY LABORATORIES LIMITED (IN) | 2005-04-07 | — | — | US | claimed |
| WO-2005021515-A2 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-10 | — | — | WO | claimed |
| US-5200516-A | Synthesis of sugars from substituted and unsubstituted arene diols | VIRGINIA TECH INTELLECTUAL PROPERTIES (US) | 1993-04-06 | — | — | US | claimed |
| EP-0220118-B1 | BICYCLIC NAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1992-01-02 | — | — | EP | claimed |
| EP-0297995-B1 | POLYCYCLIC AROMATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND ANIMAL MEDICINE AND IN COSMETICS | L'OREAL (FR) | 1991-03-06 | — | — | EP | claimed |
| US-4826969-A | SKIN AND EYE DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1989-05-02 | — | — | US | claimed |
| US-4283565-A | REACTING A BENZYL HALIDE WITH A FORMATE, CONTACTING WITH AN ALCOHOL TO TRANSESTERIFY | DYNAMIT NOBEL AG (DE) | 1981-08-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213540-A1 | Process for the hydrogenation of imines | KCNH3, KCNH2, KMO | KCNN4 256/4885ALDH1A1 1856/4885TSHR 2732/4885 |
| US-20050075383-A1 | Inhibitors of phophodiesterase type-IV | PDE7A, PDE4A, PDE4B | KCNN4 3329/4885ALDH1A1 718/4885TSHR 4144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.