Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 4/20 | 0.37 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.37 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 4/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.37 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.35 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.35 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.35 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.35 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.35 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.35 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.35 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.35 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.34 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658239 | 1.00 | PYGB (0.38) | PYGBLGALS8LGALS3LGALS4STAT3 | |
| SCHEMBL10776061 | 1.00 | PYGB (0.38) | PYGBLGALS8LGALS3LGALS4STAT3 | |
| SCHEMBL14502564 | 1.00 | PYGB (0.38) | PYGBLGALS8LGALS3LGALS4STAT3 | |
| SCHEMBL25083708 | 1.00 | PYGB (0.38) | PYGBLGALS8LGALS3LGALS4STAT3 | |
| SCHEMBL8658242 | 1.00 | PYGB (0.38) | PYGBLGALS8LGALS3LGALS4STAT3 | |
| SCHEMBL23240738 | 1.00 | PYGB (0.38) | PYGBLGALS8LGALS3LGALS4STAT3 | |
| SCHEMBL13862964 | 1.00 | PYGB (0.38) | PYGBLGALS8LGALS3LGALS4STAT3 | |
| SCHEMBL23059621 | 1.00 | PYGB (0.38) | PYGBLGALS8LGALS3LGALS4STAT3 | |
| SCHEMBL12964266 | 1.00 | PYGB (0.38) | PYGBLGALS8LGALS3LGALS4STAT3 | |
| SCHEMBL14502565 | 1.00 | PYGB (0.38) | PYGBLGALS8LGALS3LGALS4STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195430-A1 | STREPTOCOCCUS MUTANS GLUCOSYL TRANSFERASE INHIBITORS FOR DENTAL CARIES THERAPY | UAB RESEARCH FOUNDATION (US) | 2019-10-10 | — | — | WO | disclosed |
| EP-1637539-B1 | PYRAZOLE DERIVATIVE, DRUG COMPOSITION CONTAINING THE SAME AND PRODUCTION INTERMEDIATE THEREFOR | KISSEI PHARMACEUTICAL (JP) | 2012-01-18 | — | — | EP | disclosed |
| US-7888487-B2 | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof and intermediate in producing the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2011-02-15 | — | — | US | disclosed |
| US-7888487-B2 | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof and intermediate in producing the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2011-02-15 | — | — | US | disclosed |
| US-20100029919-A1 | PYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATE IN PRODUCING THE SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20100029919-A1 | PYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATE IN PRODUCING THE SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-7576064-B2 | Pyrazole derivative, drug composition containing the same and production intermediate therefor | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576064-B2 | Pyrazole derivative, drug composition containing the same and production intermediate therefor | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576063-B2 | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof and intermediate in producing the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576063-B2 | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof and intermediate in producing the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-08-18 | — | — | US | disclosed |
| US-20070060531-A1 | Pyrazole derivative, drug composition containing the same and production intermediate therefor | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
| US-20070060531-A1 | Pyrazole derivative, drug composition containing the same and production intermediate therefor | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029919-A1 | PYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATE IN PRODUCING THE SAME | SLC2A3, SLC2A1, SLC5A1 | PYGB 1380/4885LGALS8 838/4885LGALS3 505/4885 |
| US-20070060531-A1 | Pyrazole derivative, drug composition containing the same and production intermediate therefor | SLC5A1, SLC5A2, SLC2A1 | PYGB 1507/4885LGALS8 445/4885LGALS3 429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.