SCHEMBL8658239

SCHEMBL8658239

CO[C@@H]1C[C@H](O)[C@@H](O)[C@@H](CO)O1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PYGB P11216 1/20 0.38
LGALS8 O00214 4/20 0.37
LGALS3 P17931 3/20 0.37
LGALS4 P56470 1/20 0.37
STAT3 P40763 4/20 0.37
SLC5A1 P13866 1/20 0.37
ATP1A1 P05023 1/20 0.35
ATP1B1 P05026 1/20 0.35
ATP1A3 P13637 1/20 0.35
ATP1B2 P14415 1/20 0.35
ATP1A2 P50993 1/20 0.35
ATP1B3 P54709 1/20 0.35
FXYD2 P54710 1/20 0.35
ATP1A4 Q13733 1/20 0.35
LGALS1 P09382 2/20 0.34
LGALS9 O00182 1/20 0.34
MGAM O43451 2/20 0.34
SI P14410 2/20 0.34
OGA O60502 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10776061 1.00 PYGB (0.38) PYGBLGALS8LGALS3LGALS4STAT3
SCHEMBL10260244 1.00 PYGB (0.38) PYGBLGALS8LGALS3LGALS4STAT3
SCHEMBL14502564 1.00 PYGB (0.38) PYGBLGALS8LGALS3LGALS4STAT3
SCHEMBL25083708 1.00 PYGB (0.38) PYGBLGALS8LGALS3LGALS4STAT3
SCHEMBL8658242 1.00 PYGB (0.38) PYGBLGALS8LGALS3LGALS4STAT3
SCHEMBL23240738 1.00 PYGB (0.38) PYGBLGALS8LGALS3LGALS4STAT3
SCHEMBL13862964 1.00 PYGB (0.38) PYGBLGALS8LGALS3LGALS4STAT3
SCHEMBL23059621 1.00 PYGB (0.38) PYGBLGALS8LGALS3LGALS4STAT3
SCHEMBL12964266 1.00 PYGB (0.38) PYGBLGALS8LGALS3LGALS4STAT3
SCHEMBL14502565 1.00 PYGB (0.38) PYGBLGALS8LGALS3LGALS4STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4415731-A Process for the preparation of methyl 2,6-dideoxy-α-D-arabino-hexopyranoside MERCK & CO., INC. (US) 1983-11-15 US claimed
EP-0739333-B1 SELECTIVE ASYMMETRIC HYDROGENATION OF DEHYDROAMINO ACID DERIVATIVES USING RHODIUM AND IRIDIUM DIPHOSPHINITE CARBOHYDRATE CATALYST COMPOSITIONS DU PONT (US) 1998-10-14 EP disclosed
EP-0739333-A1 SELECTIVE ASYMMETRIC HYDROGENATION OF DEHYDROAMINO ACID DERIVATIVES USING RHODIUM AND IRIDIUM DIPHOSPHINITE CARBOHYDRATE CATALYST COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-10-30 EP disclosed
US-5510507-A COORDINATION CATALYSTS; EFFICIENT ENANTIOSELECTIVITY E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-04-23 US disclosed
US-5481006-A PREPARATION OF INTERMEDIATES FOR PHARMACEUTICALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-01-02 US disclosed
WO-1995018787-A1 SELECTIVE ASYMMETRIC HYDROGENATION OF DEHYDROAMINO ACID DERIVATIVES USING RHODIUM AND IRIDIUM DIPHOSPHINITE CARBOHYDRATE CATALYST COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-07-13 WO disclosed
US-4544502-A Chiral synthesis of thienamycin from D-glucose MERCK & CO., INC. (US) 1985-10-01 US disclosed
US-4491659-A 2,6-Didioxy-3-amine,4-carboxy methylglycoside and related compounds MERCK & CO., INC. (US) 1985-01-01 US disclosed
US-4448976-A Chiral synthesis of thienamycin from D-gluocose MERCK & CO., INC. (US) 1984-05-15 US disclosed
US-4415731-A Process for the preparation of methyl 2,6-dideoxy-α-D-arabino-hexopyranoside MERCK & CO., INC. (US) 1983-11-15 US disclosed
US-4415731-A Process for the preparation of methyl 2,6-dideoxy-α-D-arabino-hexopyranoside MERCK & CO., INC. (US) 1983-11-15 US disclosed
US-4384998-A Synthesis of thienamycin from D-glucose MERCK & CO., INC. (US) 1983-05-24 US disclosed
US-4324900-A 3-Amino-4-C-carboxy-2,3,4,6-tetradeoxy-D-arabino-hexose trimethylene dithioacetal MERCK & CO., INC. (US) 1982-04-13 US disclosed